Production of an ochratoxin A antigen with high hapten/carrier molar ratio.
Acta pathologica et microbiologica Scandinavica. Section C, Immunology, 86C(4), 203-204 (1978-08-01)
Benedikt Cramer et al.
Bioorganic & medicinal chemistry, 18(1), 343-347 (2009-11-19)
The mycotoxin ochratoxin A is a potent inhibitor of the protein biosynthesis and known to be cytotoxic in nanomolar concentrations. In order to investigate the relationship between stereochemistry and cytotoxicity of this compound, all four ochratoxin A stereoisomers have been...
Maria-Teresa Gutierrez-Lugo et al.
Bioorganic & medicinal chemistry letters, 21(8), 2480-2483 (2011-03-12)
The cysteinyl transferase mycothiol ligase, or MshC, catalyzes the fourth step in the biosynthesis of the small molecular weight thiol mycothiol. MshC is essential for growth of Mycobacterium tuberculosis. Two groups of known aminoacyl tRNA synthetase inhibitors were evaluated for...
Gregory Kaler et al.
The Journal of biological chemistry, 282(33), 23841-23853 (2007-06-08)
Organic anion transporters (OATs, SLC22) interact with a remarkably diverse array of endogenous and exogenous organic anions. However, little is known about the structural features that determine their substrate selectivity. We examined the substrate binding preferences and transport function of...