P1162

Sigma-Aldrich

Palmitic acid N-hydroxysuccinimide ester

≥98% (TLC)

Synonym(s):
N-(Palmitoyloxy)succinimide, N-Succinimidyl palmitate, Palmitic acid N-succinimidyl ester
Empirical Formula (Hill Notation):
C20H35NO4
CAS Number:
Molecular Weight:
353.50
Beilstein/REAXYS Number:
1547411
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

assay

≥98% (TLC)

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCCCC(=O)ON1C(=O)CCC1=O

InChI

1S/C20H35NO4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20(24)25-21-18(22)16-17-19(21)23/h2-17H2,1H3

InChI key

OTNHQVHEZCBZQU-UHFFFAOYSA-N

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Application

Palmitic acid N-hydroxysuccinimide ester has been used to couple a protein for fabrication of targeted delivery vehicles. It has also been used in the covalent attachment of palmitic acid to ovalbumin.
Useful in the synthesis of hexadecanoyl derivatives of amino- and thio-compounds such as amino acids, aminoacyl-tRNA, coenzyme A, thioglycolic acid, etc.

Packaging

1, 5 g in poly bottle

Biochem/physiol Actions

Palmitic acid N-hydroxysuccinimide ester is used in the covalent linking of protein to palmitic acid.

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Ana Rute Neves et al.
Nanotechnology, 26(49), 495103-495103 (2015-11-18)
Nanotechnology can be an important tool to improve the permeability of some drugs for the blood-brain barrier. In this work we created a new system to enter the brain by functionalizing solid lipid nanoparticles with apolipoprotein E, aiming to enhance...
Adam Edelstein et al.
Shock (Augusta, Ga.), 36(5), 451-457 (2011-09-23)
Translocation of bacteria and other luminal factors from the intestine following surgical injury can be a major driver of critical illness. Bile acids have been shown to play a key role in the loss of intestinal epithelial barrier function during...
Cell-specific siRNA delivery by peptides and antibodies
Methods in Enzymology, 502, 91-122 (2012)
Cell-specific siRNA delivery by peptides and antibodies
Test, 502, 91-122 (2012)
Preparation of immune stimulating complexes (ISCOMs) as adjuvants
Mowat AM and Reid G
Current Protocols in Immunology, 16(1), 2-11 (1995)

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