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MilliporeSigma

P1167

Sigma-Aldrich

Pituitary Extract bovine

≥95% (SDS-PAGE), lyophilized powder, suitable for cell culture

Synonym(s):

BPE, PEX

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5 MG
$73.30

About This Item

MDL number:
UNSPSC Code:
12352202
NACRES:
NA.75

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$73.30


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Product Name

Pituitary Extract bovine, lyophilized powder, suitable for cell culture

biological source

bovine

Quality Level

form

lyophilized powder

potency

15 - 200 μg/mL EC50

quality

endotoxin tested

packaging

pkg of 5 mg

technique(s)

cell culture | mammalian: suitable

impurities

≤50 EU/mg

color

brown

solubility

0.85% sodium chloride: soluble 1 vial/mL, clear to hazy, faintly yellow to dark yellow-orange

storage temp.

2-8°C

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This Item
E0760F3133F5392
biological source

bovine

biological source

bovine pituitary glands

biological source

bovine pituitary glands

biological source

bovine pituitary glands

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

lyophilized powder

form

powder

form

lyophilized powder

form

lyophilized powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

impurities

≤50 EU/mg

impurities

≤20 EU/vial (LAL test)

impurities

endotoxin, tested

impurities

<0.5 EU/vial

General description

Pituitary Extract, bovine (PEX) is an extract of bovine pituitary tissue containing growth factors.[1]

Application

Pituitary Extract bovine has been used as a component in the Roswell Park memorial institute 1640 (RPMI-1640) to culture Rb-/- epithelial cells.[2] It has also been used as a component in the Dulbecco′s modified Eagle′s medium (DMEM) for culturing Schwann cells.[3]

Biochem/physiol Actions

Pituitary Extract, bovine (PEX) or BPE is essential for mitotic activity[1] and promotes the growth of several types of mammalian cells.[4] It favors the proliferation of keratocytes culture[1] and bovine knee chondrocytes.[4] BPE helps in the synthesis of collagen and glycosaminoglycans (GAGs) in bovine knee chondrocytes.[4]

Physical form

Lyophilized from sodium phosphate buffer

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