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P1167

Sigma-Aldrich

Pituitary Extract bovine

lyophilized powder, suitable for cell culture

Synonym(s):
BPE, PEX
MDL number:

biological source

bovine

Quality Level

form

lyophilized powder

potency

15 - 200 μg/mL EC50

quality

endotoxin tested

packaging

pkg of 5 mg

technique(s)

cell culture | mammalian: suitable

impurities

≤50 EU/mg

color

brown

solubility

0.85% sodium chloride: soluble 1 vial/mL, clear to hazy, faintly yellow to dark yellow-orange

storage temp.

2-8°C

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General description

Pituitary Extract, bovine (PEX) is an extract of bovine pituitary tissue containing growth factors.

Application

Pituitary Extract bovine has been used as a component in the Roswell Park memorial institute 1640 (RPMI-1640) to culture Rb-/- epithelial cells. It has also been used as a component in the Dulbecco′s modified Eagle′s medium (DMEM) for culturing Schwann cells.

Biochem/physiol Actions

Pituitary Extract, bovine (PEX) or BPE is essential for mitotic activity and promotes the growth of several types of mammalian cells. It favors the proliferation of keratocytes culture and bovine knee chondrocytes. BPE helps in the synthesis of collagen and glycosaminoglycans (GAGs) in bovine knee chondrocytes.

Physical form

Lyophilized from sodium phosphate buffer

Certificate of Analysis

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Certificate of Origin

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SDS

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