Pluronic® F-68

solid, BioReagent, suitable for cell culture, suitable for insect cell culture

Polyoxyethylene-polyoxypropylene block copolymer
Linear Formula:
CAS Number:
MDL number:
PubChem Substance ID:
Pricing and availability is not currently available.


Contains 100 ppm BHT

product line




mol wt

average mol wt 8350


cell culture | insect: suitable
cell culture | mammalian: suitable


0.04 mM (20-25°C)





InChI key


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A non-ionic detergent that protects cells from hydrodynamic damage.

Legal Information

Pluronic is a registered trademark of BASF

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves


NONH for all modes of transport

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

  1. How does the storage temperature relate to shipping conditions?

    The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment. See Shipping and Storage for more information.

  2. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  3. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  4. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  5. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  6. What is the difference between Pluronic® F-68 Products P1300 and P7061?

    The main differences between the P1300 and the P7061 are the testing specifications, and the form in which they are provided.  The P1300 is more of a white prill/solid, and the P7061 is more of a powder.

  7. Will the P130Pluronic® F-68, Product P1300, meet NF, Clinical or Pharamaceutical specifications or not?

    The P1300 is not an NF, Clinical nor Pharamaceutical grade product; it will not necessarily meet those specifications.

  8. Can Pluronic® F-68, Product P1300, be sterilized by filtration?

    Solutions of Product No. P1300 can be filtered by using a 0.2 mm pore size filter.

  9. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

  10. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

E T Papoutsakis
Trends in biotechnology, 9(9), 316-324 (1991-09-01)
Over the past 30 years, several different additives have been used to protect freely suspended animal cells in culture from agitation and aeration damage. These include pluronic polyols, various derivatized celluloses and starches, protein mixtures, polyvinyl-pyrrolidones, dextrans, and, more recently...
Fabio Fachin et al.
Scientific reports, 7(1), 10936-10936 (2017-09-09)
Circulating tumor cells (CTCs) are a treasure trove of information regarding the location, type and stage of cancer and are being pursued as both a diagnostic target and a means of guiding personalized treatment. Most isolation technologies utilize properties of...
Renata Francielle Bombaldi de Souza et al.
International journal of biological macromolecules, 143, 619-632 (2019-12-08)
The periosteum is a membrane that surrounds bones, providing essential cellular and biological components for fracture healing and bone repair. Tissue engineered scaffolds able to function as periosteum substitutes can significantly improve bone regeneration in severely injured tissues. Efforts to...
Adolfo Cruz-Reséndiz et al.
BMC biotechnology, 20(1), 1-1 (2020-01-22)
The use of biomaterials has been expanded to improve the characteristics of vaccines. Recently we have identified that the peptide PH(1-110) from polyhedrin self-aggregates and incorporates foreign proteins to form particles. We have proposed that this peptide can be used...
Tsz Chung Lai et al.
Colloids and surfaces. B, Biointerfaces, 99, 27-37 (2011-10-18)
Polyplex particles formed with plasmid DNA (pDNA) and Pluronic P85-block-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} (P85-b-P[Asp(DET)]) demonstrated highly effective transfection ability compared to PEG-based block cationomer, PEG-b-P[Asp(DET)]. Ternary polyplexes comprising PEG-b-P[Asp(DET)], poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide)-b-P[Asp(DET)] (P(EPE)-b-P[Asp(DET)]) used as an analog of P85-b-P[Asp(DET)], and pDNA were...

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