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P148

Sigma-Aldrich

4α-Phorbol 12-myristate 13-acetate

solid, ≥95% (TLC)

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Synonym(s):
4α-PMA
Empirical Formula (Hill Notation):
C36H56O8
CAS Number:
Molecular Weight:
616.83
MDL number:
PubChem Substance ID:
NACRES:
NA.77

Quality Level

assay

≥95% (TLC)

form

solid

color

white

solubility

H2O: ~2 μM (Though having aqueous solubility, it is recommended that this compound first be dissolved in a water miscible organic solvent before dilution to working concentrations in aqueous media.)
DMSO: soluble
ethanol: soluble

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@@]2(O)C(C=C(CO)C[C@]3(O)C2C=C(C)C3=O)C4C(C)(C)[C@]14OC(C)=O

InChI

1S/C36H56O8/c1-7-8-9-10-11-12-13-14-15-16-17-18-29(39)43-32-24(3)35(42)27(30-33(5,6)36(30,32)44-25(4)38)20-26(22-37)21-34(41)28(35)19-23(2)31(34)40/h19-20,24,27-28,30,32,37,41-42H,7-18,21-22H2,1-6H3/t24-,27+,28-,30-,32-,34+,35-,36-/m1/s1

InChI key

PHEDXBVPIONUQT-LQLWEASQSA-N

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1 of 4

This Item
P813979346C2020
4α-Phorbol 12-myristate 13-acetate solid, ≥95% (TLC)

P148

4α-Phorbol 12-myristate 13-acetate

Phorbol 12-myristate 13-acetate ≥99% (TLC), film or powder

P8139

Phorbol 12-myristate 13-acetate

Phorbol 12-myristate 13-acetate synthetic, ≥98.0% (TLC)

79346

Phorbol 12-myristate 13-acetate

α-Cyano-4-hydroxycinnamic acid ≥98% (TLC), powder

C2020

α-Cyano-4-hydroxycinnamic acid

assay

≥95% (TLC)

assay

≥99% (TLC)

assay

≥98.0% (TLC)

assay

≥98% (TLC)

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

solubility

H2O: ~2 μM (Though having aqueous solubility, it is recommended that this compound first be dissolved in a water miscible organic solvent before dilution to working concentrations in aqueous media.), ethanol: soluble, DMSO: soluble

solubility

DMSO: soluble (Dissolve in water-miscible organic solvent prior to preparing aqueous solutions. DMSO solutions can be stored dark at -20 °C for at least six months.), ethanol: soluble (Dissolve in water-miscible organic solvent prior to preparing aqueous solutions.)

solubility

chloroform: 10 mg/mL, clear, colorless to light yellow

solubility

H2O: slightly soluble, methanol: water: soluble, polar organic solvents: soluble

color

white

color

-

color

-

color

yellow

Biochem/physiol Actions

Negative control for phorbol ester activation of protein kinase C.

Packaging

Sealed glass ampule.

Caution

Photosensitive

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Journal of neurochemistry, 48(2), 615-621 (1987-02-01)
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