P1614

Sigma-Aldrich

Protein kinase Cζ pseudosubstrate, myristoyl trifluoroacetate salt

≥90% (HPLC)

Synonym(s):
ZIP, PKC Zeta Pseudosubstrate Inhibitory peptide
MDL number:
NACRES:
NA.77

Quality Level

assay

≥90% (HPLC)

mol wt

calculated mol wt 1928

solubility

H2O: soluble

storage temp.

−20°C

Amino Acid Sequence

Myr-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg--Arg-Trp-Arg-Lys-Leu

Biochem/physiol Actions

Cell permeable protein kinase C (PKC) ζ inhibitor.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
P M Dang et al.
Journal of immunology (Baltimore, Md. : 1950), 166(2), 1206-1213 (2001-01-06)
Generation of superoxide anion by the multiprotein complex NADPH phagocyte oxidase is accompanied by extensive phosphorylation of its 47-kDa protein component, p47(phox), a major cytosolic component of this oxidase. Protein kinase C zeta (PKC zeta), an atypical PKC isoform expressed...
Miguel Salinas-Saavedra et al.
eLife, 7 (2018-08-01)
In triploblastic animals, Par-proteins regulate cell-polarity and adherens junctions of both ectodermal and endodermal epithelia. But, in embryos of the diploblastic cnidarian Nematostella vectensis, Par-proteins are degraded in all cells in the bifunctional gastrodermal epithelium. Using immunohistochemistry, CRISPR/Cas9 mutagenesis, and...

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