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P1625

Sigma-Aldrich

Pancreatin from porcine pancreas

≥3 × USP specifications

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Synonym(s):
Pancreatin from hog pancreas
CAS Number:
EC Number:
MDL number:
NACRES:
NA.54

biological source

Porcine pancreas

Quality Level

agency

USP (specifications)

form

powder

specific activity

≥3 × USP specifications

storage temp.

−20°C

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Pancreatin from porcine pancreas ≥3 × USP specifications

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Pancreatin from porcine pancreas 4 × USP specifications

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P7545

Pancreatin from porcine pancreas

Pancreatin from porcine pancreas powder, suitable for cell culture, 4 × USP specifications

P3292

Pancreatin from porcine pancreas

biological source

Porcine pancreas

biological source

-

biological source

-

biological source

Porcine pancreas

form

powder

form

powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

agency

USP (specifications)

agency

USP (specifications)

agency

-

agency

USP (specifications)

Application

Pancreatin from porcine pancreas is suitable:
  • in a study to assess the treatment of steatorrhea by lipase supplementation therapy
  • in a study to investigate treatment options for pancreatic diabetes in patients experiencing the decompensated stage of chronic pancreatitis
  • to safely and effectively remove formalin-fixed tissues from arterial grafts without causing structural damage and loss in fiber integrity.
  • to assess cleavage by digestive enzymes. It is used for in vitro digestibility analysis and to test the sensitivities of cellulolytic bacteria inhibitors
  • along with amyloglucosidase for the in vitro digestion of starch in food samples

Biochem/physiol Actions

Pancreatin contains enzymatic components including trypsin, amylase and lipase, ribonuclease, and protease, produced by the exocrine cells of the porcine pancreas. This combination of enzymes allows it to hydrolyze proteins, starch and fats. Pancreatin will convert not less than 25 times its weight of potato starch into soluble carbohydrates in 5 minutes in water at 40°C, will digest not less than 25 times its weight of casein in 60 minutes at pH 7.5 at 40°C and will release not less than microequivalents of acid per min per mg pancreatin from olive oil at pH 9.0 at 37°C.

pictograms

Exclamation markHealth hazard

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1


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R Raghunathan et al.
Food chemistry, 221, 1514-1521 (2016-12-17)
The objective of this study was to determine the molecular structure and properties of recently released cultivars of field peas [CDC Golden (CDCG), Abarth (ABAR), CDC Patrick (CDCP) and CDC Amarillo (CDCA)] grown at different locations in Saskatchewan, Canada. Starch
Cunxi Wang et al.
Regulatory toxicology and pharmacology : RTP, 71(2), 164-173 (2014-12-30)
DroughtGard maize was developed through constitutive expression of cold shock protein B (CSPB) from Bacillus subtilis to improve performance of maize (Zea mays) under water-limited conditions. B. subtilis commonly occurs in fermented foods and CSPB has a history of safe
Peter Layer et al.
Pancreas, 26(1), 1-7 (2002-12-25)
Treatment of steatorrhea by lipase supplementation therapy has become more successful in the last decade due to better understanding of the physiology and pathophysiology of the digestive process. Porcine lipase has been the therapeutic standard for several decades and will
Ruixin Zhu et al.
Nutrients, 11(3) (2019-03-17)
Plant origin, processing, and domestic preparation may affect the postprandial glycemic response (PGR) of starchy foods. The objective of this study was to examine the possibility of integrating domestically cooked non-cereal starchy foods commonly consumed in Northeast Asia into glycemic
T Nakamura et al.
Pancreas, 16(3), 329-336 (1998-04-21)
Pancreatic steatorrhea and pancreatic diabetes are the dominant symptoms of patients in the decompensated stage of chronic pancreatitis (CP). In this stage, the nutritional state is greatly disturbed and hypoglycemia and labile infection are involved. Pancreatic enzyme replacement therapy is

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