Stock solutions are stable for up to 2 weeks when stored refrigerated at 4°C and up to 6 months when stored in aliquots at -20°C. Avoid repeated freeze/thaw cycles.
P1742
Prealbumin from human plasma
lyophilized powder
Synonym(s):
Thyroxine binding prealbumin, Transthyretin
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0.5 MG
$300.00
1 MG
$520.00
5 MG
$2,030.00
About This Item
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biological source
human plasma
Quality Level
assay
≥95% (SDS-PAGE)
form
lyophilized powder
technique(s)
immunoelectrophoresis: suitable
immunoprecipitation (IP): suitable
impurities
Infectious agents, tested
solubility
H2O: soluble 1 mg/mL
ε (extinction coefficient)
13.5 at 280 nm at 1%
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... TTR(7276)
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This Item | A1887 | A8849 | G9885 |
|---|---|---|---|
| assay ≥95% (SDS-PAGE) | assay ≥96% (agarose gel electrophoresis) | assay - | assay ≥99% (agarose gel electrophoresis) |
| technique(s) immunoelectrophoresis: suitable, immunoprecipitation (IP): suitable | technique(s) ELISA: suitable, tissue culture: suitable, western blot: suitable | technique(s) - | technique(s) ELISA: suitable |
| biological source human plasma | biological source human | biological source human plasma | biological source human plasma |
| Quality Level 200 | Quality Level 300 | Quality Level 200 | Quality Level 200 |
| form lyophilized powder | form lyophilized powder | form lyophilized powder | form powder |
| impurities Infectious agents, tested | impurities HIV I and HIVII, HCV and HBsAg, tested negative, ≤0.007% Fatty Acids | impurities - | impurities HIV-1/HIV-2, HCV and hepatitis B antigen, tested negative |
General description
Human prealbumin is a product of chromosome 18. It is a serum protein, synthesized primarily in the liver.[1] It is a tetrameric protein with a molecular weight of 55 kDa. Human prealbumin is composed of four identical non-covalently bound monomers of 127 amino acid residues arranged with tetrahedral symmetry.[2]
Application
Human prealbumin was used to study reduced transthyretin expression in sera of lung cancer.[3]
Biochem/physiol Actions
Human prealbumin has been observed in carcinoid tumors.[1]
Packaging
Package size based on protein content
Physical form
Lyophilized powder containing sodium phosphate and NaCl
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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David Adams et al.
Presse medicale (Paris, France : 1983), 41(9 Pt 1), 793-806 (2012-02-22)
The treatment of familial amyloid polyneuropathies (FAP) is complex and requires a neurological and cardiological multidisciplinary coverage. It includes specific treatments to control the progression of the systemic amyloidogenesis, the symptomatic treatment of the peripheral and autonomic neuropathy (digestive, urinary
J P Hegmann
Behavior genetics, 9(3), 165-175 (1979-05-01)
Behavioral and physiological scores from 697 mice sampled from lines at various times during their response to bidirectional selection for divergent caudal nerve conduction velocity suggest broad-reaching behavioral effects of the gene differences among lines. Sciatic nerve conduction velocity differences
J Figueras et al.
Medicina clinica, 116(10), 377-379 (2001-05-03)
Domino or sequential liver transplantation (DTXL) is a kind of living donor transplant, which was proposed in 1993 and performed for the first time in 1995; later on, more than 45 have been reported. The liver from a patient with
Minori Kodaira et al.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 18(1), 10-18 (2011-01-26)
The process of deterioration of peripheral nerve function in familial amyloid polyneuropathy (FAP) with amyloidogenic transthyretin (ATTR) Val30Met has not been systematically evaluated hitherto. We performed nerve conduction studies in 69 patients with FAP with ATTR Val30Met from one of
K Tashima et al.
Journal of the neurological sciences, 171(1), 19-23 (1999-11-24)
Since 1990, liver transplantation for familial amyloidotic polyneuropathy (FAP) has been carried out world-wide, and the outcome of the procedure seems to be promising. FAP is inherited systemic disease caused by mutated transthyretin. The most common cause is the valine
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How long does prealbumin from human plasma (product P1742) remain stable after being dissolved in water, and at what temperature should this solution be stored?
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What is the molecular weight of Product P1742, Prealbumin from human plasma?
1 answer-
The molecular weight has been reported to be 54,980 Daltons. Referece: The Plasma Proteins, 2nd edition (1975) p. 60.
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What is the volume from which Product P1742, Prealbumin from human plasma, is lyophilized from?
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The starting volume is lot specific. Please contact Technical Service to obtain the exact volume of your lot of interest.
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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What is the purity of Product P1742, Prealbumin from human plasma?
1 answer-
Information about purity can be found on the lot specific certificate of analysis.
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What is the solubility of Product P1742, Prealbumin from human plasma?
1 answer-
This product is soluble in water at 1mg/mL.
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