P2443

Pluronic^® F-127

powder, BioReagent, suitable for cell culture

• Synonym(s): Non-ionic copolymer surfactant
• Linear Formula: (C₃H₆O·C₂H₄O)x
• CAS Number: 9003-11-6
• MDL number: MFCD00082049
• PubChem Substance ID: 24897874
• NACRES: NA.75

Properties

• description: Non-ionic; contains 100ppm BHT
• Quality Level: 200
• product line: BioReagent
• form: powder
• mol wt: ~12600 g/mol
• technique(s): cell culture | mammalian: suitable
• CMC: 950-1000 ppm (~25°C)
• transition temp: cloud point >100 °C
• HLB: 18 - 23
• InChI: 1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
• InChI key: RVGRUAULSDPKGF-UHFFFAOYSA-N

Description

Application

A non-ionic copolymer surfactant qualified for use in insect cell culture applications as an antifoaming agent.

Pluronic^® F-127 was used to coat a siliconized coverslip to hold an egg extract in a study. Pluronic F-127 was added to phosphate buffered saline (PBS), to lower unspecific cell and protein adhesion to a PDMS-based microfluidic device. A study reports its use as a release vehicle to transport low-dose perivascular lipopolysaccharide (LPS) on mouse vein grafts. PLGA/pluronic F127 may be used to fabricate nerve guidance conduits (NGCs) for regeneration of peripheral nerve. Fabrication of poly (lactide-co-glycolide) (PLGA) — Pluronic F127 glass composites was reported. Pluronic F-127 was used for fluorescent labeling of blood vessels, astrocytes, and neurons.

Packaging

250, 500 g

1 kg in poly bottle

Legal Information

Pluronic is a registered trademark of BASF

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves