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P3662

Sigma-Aldrich

Sodium pyruvate

Hybri-Max, powder, suitable for hybridoma

Synonym(s):
α-Ketopropionic acid sodium salt, 2-Oxopropanoic acid sodium salt, Pyruvic acid sodium salt
Linear Formula:
CH3COCOONa
CAS Number:
Molecular Weight:
110.04
Beilstein:
3568341
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.75

biological source

synthetic (organic)

Quality Level

grade

Hybri-Max

Assay

≥99%

form

powder

technique(s)

cell culture | hybridoma: suitable

impurities

endotoxin, tested

mp

>300 °C (lit.)

solubility

H2O: 100 mg/mL

shipped in

ambient

storage temp.

2-8°C

SMILES string

[Na+].CC(=O)C([O-])=O

InChI

1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1

InChI key

DAEPDZWVDSPTHF-UHFFFAOYSA-M

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P2256P8574792500
Sodium pyruvate Hybri-Max™, powder, suitable for hybridoma

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Sodium pyruvate

Sodium pyruvate ReagentPlus®, ≥99%

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Sodium pyruvate

Sodium pyruvate BioXtra, ≥99%

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P8574

Sodium pyruvate

Sodium pyruvate anhydrous, free-flowing, Redi-Dri™, ReagentPlus®, ≥99%

Sigma-Aldrich

792500

Sodium pyruvate

grade

Hybri-Max

grade

-

grade

-

grade

anhydrous

form

powder

form

powder

form

powder

form

powder

technique(s)

cell culture | hybridoma: suitable

technique(s)

-

technique(s)

-

technique(s)

-

impurities

endotoxin, tested

impurities

-

impurities

≤0.005% Phosphorus (P), ≤0.1% Insoluble matter

impurities

-

solubility

H2O: 100 mg/mL

solubility

H2O: 100 mg/mL, clear, colorless to faintly yellow

solubility

H2O: 1 M, clear, colorless

solubility

H2O: 100 mg/mL, clear, colorless to faintly yellow

Application

Sodium pyruvate has been used as a component in maturation medium for oocyte evaluation.
Sodium pyruvate is used by cells as an easily accessible carbohydrate source. Additionally, it is involved with amino acid metabolism and initiates the Kreb′s cycle. The 100 mM solution should be diluted 1:100 for most cell culture applications.

Biochem/physiol Actions

Sodium pyruvate is known to be an effective therapeutic target for type II citrullinaemia which is characterized by hyperammonaemia. In vivo studies proves that sodium pyruvate has protective function against hemorrhagic shock by preventing lipid peroxidation, NAD+ reduction and cleavage of poly(ADP-ribose) polymerases. Sodium pyruvate is also known to possess anti-inflammatory action and might show improvement in chronic lung disorder.

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1B

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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25G
Pack Size/Quantity

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Essence of Anesthesia Practice: Expert Consult-Online and Print, 685-685 (2010)
Ovum pick up and in vitro embryo production in cows superstimulated with an individually adapted superstimulation protocol
De R, et al.
Animal Reproduction Science, 86(1-2), 13-25 (2005)
Treatment of a citrin-deficient patient at the early stage of adult-onset type II citrullinaemia with arginine and sodium pyruvate
Mutoh K, et al.
Journal of inherited metabolic disease, 31(2), 343-347 (2008)
Characterisation of low, medium and high responders following FSH stimulation prior to ultrasound-guided transvaginal oocyte retrieval in cows
De RR, et al.
Animal Reproduction Science, 63(7), 1902-1913 (2005)
Metabolic and histologic effects of sodium pyruvate treatment in the rat after cortical contusion injury
Fukushima M, et al.
Journal of Neurotrauma, 26(7), 1095-1110 (2009)

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