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Paraplast Plus®

for tissue embedding

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Paraffin – polyisobutylene mixture
CAS Number:
EC Number:
MDL number:




56-57 °C (lit.)
56-57 °C



storage temp.

room temp

General description

Paraplast Plus® is a tissue embedding medium comprising highly purified paraffin and polyisobutylene with approximately 0.8% DMSO added to improve infiltration, sectioning, and penetration into tissues. It is recommended for tissues that are difficult to process with regular Paraplast®. Paraplast Plus® cuts continuous ribbons at 2μm thickness or short ribbons at 1μm thickness.


  • Paraplast Plus® has been used in the examination of vertebral specimens of Malacoraja senta.
  • It has also been used in the identification and expression analysis of PIN genes in rice.
  • It has been used in the study of glucose transport mechanisms in uterine tissues during pregnancy.
  • It has been used to embed Bouin′s fixed carp tissues, rat ventral prostatic fragments, and common bean (Phaseolus vulgaris L.) nodules.

Legal Information

Paraplast is a registered trademark of Leica Biosystems
Paraplast Plus is a registered trademark of Leica Biosystems

Storage Class Code

11 - Combustible Solids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Harmful effects of carbamazepine on the postnatal development of the rat ventral prostate
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Reproductive Biology and Endocrinology (2012)
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Theriogenology, 105, 97-106 (2017-09-25)
Ovarian tissue transplantation could be a valuable technique for the preservation of endangered animals. The domestic cat affords an adequate experimental model for studies aimed at wild felids due to its phylogenetic similarity. Thus, this pilot study evaluated the efficacy
Shuaibin Zhang et al.
Scientific reports, 6, 23173-23173 (2016-03-19)
Early fruit development is crucial for crop production in tomato. After fertilization, the ovary undergoes cell division and cell expansion before maturation. Although the roles of regulatory signals such as hormone and carbohydrate during early fruit development have been studied
Effect of copper nanoparticles exposure in the physiology of the common carp (Cyprinus carpio): Biochemical, histological and proteomic approaches
Yugantak Raj Gupta
Aquaculture International (2017)
Micro-morphology of common bean (Phaseolus vulgaris L.)
nodules undergoing senescence
Fabia'n Ferna'ndez-Luquen?o ? L.
Acta Physiologiae Plantarum / Polish Academy of Sciences, Committee of Plant Physiology Genetics and Breeding (2008)

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Three-dimensional (3D) printing of biological tissue is rapidly becoming an integral part of tissue engineering.

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