P4562

Sigma-Aldrich

Sodium pyruvate

powder, BioXtra, suitable for mouse embryo cell culture

Synonym(s):
Pyruvic acid sodium salt, α-Ketopropionic acid sodium salt, 2-Oxopropanoic acid sodium salt
Linear Formula:
CH3COCOONa
CAS Number:
Molecular Weight:
110.04
Beilstein/REAXYS Number:
3568341
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.75

Quality Level

product line

BioXtra

assay

≥99%

form

powder

application(s)

cell culture | embryo: suitable

mp

>300 °C (lit.)

solubility

H2O: 100 mg/mL

storage temp.

2-8°C

SMILES string

[Na+].CC(=O)C([O-])=O

InChI

1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1

InChI key

DAEPDZWVDSPTHF-UHFFFAOYSA-M

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Application

Sodium pyruvate is used by cells as an easily accessible carbohydrate source. Additionally, it is involved with amino acid metabolism and initiates the Kreb′s cycle. Sodium pyruvate attenuates oxidative stress in vitro. The 100 mM solution should be diluted 1:100 for most cell culture applications. This product has been qualified for use in mouse embryo cultures.

Packaging

5, 25, 100 g in poly bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

hazcat

Eye Irrit. 2 - Skin Sens. 1B

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Rekin's Janky et al.
PLoS computational biology, 10(7), e1003731-e1003731 (2014-07-25)
Identifying master regulators of biological processes and mapping their downstream gene networks are key challenges in systems biology. We developed a computational method, called iRegulon, to reverse-engineer the transcriptional regulatory network underlying a co-expressed gene set using cis-regulatory sequence analysis....
Wei Yang et al.
Nature communications, 5, 3818-3818 (2014-05-03)
Polycomb Repressive Complex 1 and histone H2A ubiquitination (ubH2A) contribute to embryonic stem cell (ESC) pluripotency by repressing lineage-specific gene expression. However, whether active deubiquitination co-regulates ubH2A levels in ESCs and during differentiation is not known. Here we report that...
Athanasia E Christakou et al.
Lab on a chip, 15(15), 3222-3231 (2015-07-02)
We demonstrate a simple method for three-dimensional (3D) cell culture controlled by ultrasonic standing waves in a multi-well microplate. The method gently arranges cells in a suspension into a single aggregate in each well of the microplate and, by this...
Lotta Tengroth et al.
PloS one, 9(6), e98239-e98239 (2014-06-03)
The human nasal epithelium is an important physical barrier, and a part of the innate immune defense that protect against pathogens. The epithelial cells recognize microbial components by pattern-recognition receptors (PRRs), and thereby trigger an immune response. Even though TLR3...
Yoh Arita et al.
Nature communications, 5, 4552-4552 (2014-07-30)
The origin and developmental mechanisms underlying coronary vessels are not fully elucidated. Here we show that myocardium-derived angiopoietin-1 (Ang1) is essential for coronary vein formation in the developing heart. Cardiomyocyte-specific Ang1 deletion results in defective formation of the subepicardial coronary...
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Mouse embryo media and embryo validated reagents for transgenic mouse embryo culture
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