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P5110

Sigma-Aldrich

Anti-Presenilin-1 (303-316) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

MDL number:
Pricing and availability is not currently available.

biological source

rabbit

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

rat, mouse

application(s)

indirect immunofluorescence: suitable
western blot: suitable

conjugate

unconjugated

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

Gene Information

mouse ... Psen1(19164)
rat ... Psen1(29192)

Immunogen

synthetic peptide corresponding to amino acids 303-316 of the loop region of mouse presenilin 1.

Physical form

Solution in 0.05 M sodium phosphate buffer containing 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK Germany

2

R Sherrington et al.
Nature, 375(6534), 754-760 (1995-06-29)
Some cases of Alzheimer's disease are inherited as an autosomal dominant trait. Genetic linkage studies have mapped a locus (AD3) associated with susceptibility to a very aggressive form of Alzheimer's disease to chromosome 14q24.3. We have defined a minimal cosegregating...
Ruben Vidal et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 26(7), 2899-2910 (2012-03-31)
Genetically engineered mice have been generated to model cerebral β-amyloidosis, one of the hallmarks of Alzheimer disease (AD) pathology, based on the overexpression of a mutated cDNA of the amyloid-β precursor protein (AβPP) or by knock-in of the murine Aβpp...

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