Gaetano R Barile et al.
Investigative ophthalmology & visual science, 46(8), 2916-2924 (2005-07-27)
The receptor for advanced glycation end products (AGEs) has been implicated in the pathogenesis of diabetic complications. This study was conducted to characterize the role of the RAGE axis in a murine model of nonproliferative diabetic retinopathy (NPDR). The retinas...
Improving thermostability of papain through structure-based protein engineering
Choudhury D, et al.
Protein engineering, design & selection : PEDS, 23(6), 457-467 (2010)
Amy Wernimont et al.
PloS one, 4(4), e5094-e5094 (2009-04-09)
For every 100 purified proteins that enter crystallization trials, an average of 30 form crystals, and among these only 13-15 crystallize in a form that enables structure determination. In 2007, Dong et al reported that the addition of trace amounts...
Jan Willem van Rijswijk et al.
The Journal of thoracic and cardiovascular surgery, 160(4), e201-e215 (2020-03-11)
Decellularized extracellular matrix made from porcine small intestinal submucosa, commercially available as CorMatrix (CorMatrix Cardiovascular, Inc, Roswell, Ga) is used off-label to reconstruct heart valves. Recently, surgeons experienced failures and words of caution were raised. The aim of this study...
Papain, a plant enzyme of biological importance: a review
Ezekiel A and Florence M
American Journal of Biochemistry and Biotechnology, 8(2), 99-104 (2012)