P5556

Sigma-Aldrich

Poloxamer 188 solution

10%, sterile-filtered, BioReagent, suitable for insect cell culture

CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.75

description

non-ionic

Quality Level

sterility

sterile-filtered

product line

BioReagent

mol wt

average mol wt 8350

concentration

10%

application(s)

cell culture | insect: suitable

impurities

endotoxin, tested

CMC

0.04 mM

transition temp

cloud point ≥100

HLB

29

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI key

RVGRUAULSDPKGF-UHFFFAOYSA-N

Related Categories

General description

Poloxamer 188 (P188) is a copolymer of polyoxyethylene and polyoxypropylene.{15} P-188 exhibits low toxicity and therefore may be used in oral drug delivery.{14}

Application

Poloxamer 188 solution is used in flow cytometry of Chinese hamster ovary (CHO) cells.{13} It was used to supplement the growth medium for MSCs (EMD Millipore SCR108) cultures. 2 bioavailability of the suspension of ketoprofen and P-188 was reported in a study.{14}
A nonionic copolymer surfactant

Legal Information

Pluronic is a registered trademark of BASF

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Dina Mourad Saleh et al.
Particle and fibre toxicology, 17(1), 48-48 (2020-10-16)
Multi-walled carbon nanotubes can be divided into two general subtypes: tangled and straight. MWCNT-N (60 nm in diameter) and MWCNT-7 (80-90 nm in diameter) are straight-type MWCNTs, and similarly to asbestos, both are carcinogenic to the lung and pleura when administered to...
Rahul P Bakshi et al.
Nature communications, 9(1), 315-315 (2018-01-24)
Chemoprophylaxis is currently the best available prevention from malaria, but its efficacy is compromised by non-adherence to medication. Here we develop a long-acting injectable formulation of atovaquone solid drug nanoparticles that confers long-lived prophylaxis against Plasmodium berghei ANKA malaria in...
Kerwin Kwek Zeming et al.
Lab on a chip, 20(18), 3445-3460 (2020-08-15)
In vitro erythroid cultures from human hematopoietic stem cells produce immature red blood cells (RBCs) called reticulocytes, which are important for RBCs production, and are widely used in scientific studies of malaria pathology, hematological diseases and protein translation. However, in...
Mimi R Borrelli et al.
Aesthetic surgery journal, 40(4), 369-379 (2019-04-12)
Breast capsular contracture is a major problem following implant-based breast reconstruction, particularly in the setting of radiation therapy. Recent work has identified a fibrogenic fibroblast subpopulation characterized by CD26 surface marker expression. This work aimed to investigate the role of...
Deshka S Foster et al.
Nature communications, 11(1), 4061-4061 (2020-08-15)
Adhesions are fibrotic scars that form between abdominal organs following surgery or infection, and may cause bowel obstruction, chronic pain, or infertility. Our understanding of adhesion biology is limited, which explains the paucity of anti-adhesion treatments. Here we present a...

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