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P5561

Sigma-Aldrich

Propionic acid

BioReagent, suitable for insect cell culture, ~99%

Synonym(s):
Acid C3, Propanoic acid, Propanyl acid
Linear Formula:
CH3CH2COOH
CAS Number:
Molecular Weight:
74.08
Beilstein:
506071
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.71

vapor density

2.55 (vs air)

vapor pressure

2.4 mmHg ( 20 °C)

product line

BioReagent

Assay

~99%

autoignition temp.

955 °F

expl. lim.

12.1 %

technique(s)

cell culture | insect: suitable

refractive index

n20/D 1.386 (lit.)

bp

141 °C (lit.)

mp

−24-−23 °C (lit.)

solubility

H2O: soluble

density

0.99 g/mL at 25 °C (lit.)
0.993 g/mL at 25 °C (lit.)

SMILES string

CCC(O)=O

InChI

1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)

InChI key

XBDQKXXYIPTUBI-UHFFFAOYSA-N

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This Item
W2924194029071572208
Propionic acid BioReagent, suitable for insect cell culture, ~99%

Sigma-Aldrich

P5561

Propionic acid

Propionic acid natural, 99%, FG

Sigma-Aldrich

W292419

Propionic acid

Propionic acid ACS reagent, ≥99.5%

Sigma-Aldrich

402907

Propionic acid

Propionic acid United States Pharmacopeia (USP) Reference Standard

USP

1572208

Propionic acid

vapor pressure

2.4 mmHg ( 20 °C)

vapor pressure

2.4 mmHg ( 20 °C)

vapor pressure

2.4 mmHg ( 20 °C)

vapor pressure

2.4 mmHg ( 20 °C)

assay

~99%

assay

99%

assay

≥99.5%

assay

-

refractive index

n20/D 1.386 (lit.)

refractive index

n20/D 1.386 (lit.)

refractive index

n20/D 1.386 (lit.)

refractive index

n20/D 1.386 (lit.)

bp

141 °C (lit.)

bp

141 °C (lit.)

bp

141 °C (lit.)

bp

141 °C (lit.)

mp

−24-−23 °C (lit.)

mp

−24-−23 °C (lit.)

mp

−24-−23 °C (lit.)

mp

−24-−23 °C (lit.)

General description

Propionic acid (PA) is a naturally occurring carboxylic acid, which in its pure state exists as a colorless corrosive liquid with an unpleasant odor. It is miscible in water. Industrially it is produced by hydrocarboxylation of ethylene in presence nickel carbonyl as a catalyst. PA has been found to reduce food intake, lower the fatty acids content in plasma and liver, might improve tissue insulin sensitivity and exerts immunosuppressive actions. Propionic acid is an excellent raw material as it is stable, cheap and safe and can even be used as a food additive.

Application

Use in insect cell culture to inhibit mold growth.

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

129.2 °F - closed cup

Flash Point(C)

54 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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25G
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Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms
Sa'ad, H., et al.
Molecular and Cellular Biology, 1801 (11), 1175-1183 (2010)
Nucleophilic ?-Carbon Activation of Propionic Acid as a 3-Carbon Synthon by Carbene Organocatalysis
Jin, Zhichao, et al.
Chemistry?A European Journal , 21 (26), 9360-9363 (2015)
Flour and Breads and their Fortification in Health and Disease Prevention.
Victor R. Preedy, Ronald Ross Watson, Vinood B
Technology & Engineering, 476-476 (2011)
Sa'ad H Al-Lahham et al.
Biochimica et biophysica acta, 1801(11), 1175-1183 (2010-08-10)
Undigested food is fermented in the colon by the microbiota and gives rise to various microbial metabolites. Short-chain fatty acids (SCFA), including acetic, propionic and butyric acid, are the principal metabolites produced. However, most of the literature focuses on butyrate
L B Bindels et al.
British journal of cancer, 107(8), 1337-1344 (2012-09-15)
Metabolites released by the gut microbiota may influence host metabolism and immunity. We have tested the hypothesis that inulin-type fructans (ITF), by promoting microbial production of short-chain fatty acids (SCFA), influence cancer cell proliferation outside the gut. Mice transplanted with

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