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P5561

Sigma-Aldrich

Propionic acid

BioReagent, suitable for insect cell culture, ~99%

Synonym(s):

Acid C3, Propanoic acid, Propanyl acid

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About This Item

Linear Formula:
CH3CH2COOH
CAS Number:
Molecular Weight:
74.08
Beilstein/REAXYS Number:
506071
EC Number:
MDL number:
UNSPSC Code:
12352207
PubChem Substance ID:
NACRES:
NA.71

vapor density

2.55 (vs air)

Quality Level

vapor pressure

2.4 mmHg ( 20 °C)

product line

BioReagent

assay

~99%

autoignition temp.

955 °F

expl. lim.

12.1 %

technique(s)

cell culture | insect: suitable

refractive index

n20/D 1.386 (lit.)

bp

141 °C (lit.)

mp

−24-−23 °C (lit.)

solubility

H2O: soluble

density

0.99 g/mL at 25 °C (lit.)
0.993 g/mL at 25 °C (lit.)

SMILES string

CCC(O)=O

InChI

1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)

InChI key

XBDQKXXYIPTUBI-UHFFFAOYSA-N

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General description

Propionic acid (PA) is a naturally occurring carboxylic acid, which in its pure state exists as a colorless corrosive liquid with an unpleasant odor. It is miscible in water. Industrially it is produced by hydrocarboxylation of ethylene in presence nickel carbonyl as a catalyst. PA has been found to reduce food intake, lower the fatty acids content in plasma and liver, might improve tissue insulin sensitivity and exerts immunosuppressive actions. Propionic acid is an excellent raw material as it is stable, cheap and safe and can even be used as a food additive.

Application

Use in insect cell culture to inhibit mold growth.

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - STOT SE 3

target_organs

Respiratory system

wgk_germany

WGK 1

flash_point_f

closed cup

flash_point_c

closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


Certificates of Analysis (COA)

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Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms
Sa'ad, H., et al.
Molecular and Cellular Biology, 1801 (11), 1175-1183 (2010)
Nucleophilic ?-Carbon Activation of Propionic Acid as a 3-Carbon Synthon by Carbene Organocatalysis
Jin, Zhichao, et al.
Chemistry?A European Journal , 21 (26), 9360-9363 (2015)
Flour and Breads and their Fortification in Health and Disease Prevention.
Victor R. Preedy, Ronald Ross Watson, Vinood B
Technology & Engineering, 476-476 (2011)
L B Bindels et al.
British journal of cancer, 107(8), 1337-1344 (2012-09-15)
Metabolites released by the gut microbiota may influence host metabolism and immunity. We have tested the hypothesis that inulin-type fructans (ITF), by promoting microbial production of short-chain fatty acids (SCFA), influence cancer cell proliferation outside the gut. Mice transplanted with
Weiqiang Chen et al.
Journal of virology, 89(1), 581-593 (2014-10-24)
The recent global resurgence of arthritogenic alphaviruses, in particular chikungunya virus (CHIKV), highlights an urgent need for the development of therapeutic intervention strategies. While there has been significant progress in defining the pathophysiology of alphaviral disease, relatively little is known

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