Palmitic acid

BioXtra, ≥99%

NSC 5030, Cetylic acid, 1-Pentadecanecarboxylic acid, Hexadecanoic acid, PamOH, C16:0
Linear Formula:
CAS Number:
Molecular Weight:
Beilstein/REAXYS Number:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

biological source

plant (vegetable)

vapor pressure

10 mmHg ( 210 °C)

product line







cell culture | mammalian: suitable


≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

ign. residue



271.5 °C/100 mmHg (lit.)


61-62.5 °C (lit.)


chloroform: 0.5 M, clear, colorless


0.852 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

functional group

carboxylic acid

shipped in


storage temp.

room temp

SMILES string




InChI key


Gene Information

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Palmitic acid has been used:
  • as a medium supplement in chorionic villous tissue culture form placenta
  • as a component of hormone pellet for implantation in mice ovary
  • for inducing expression of immunity-related GTPase M (IRGM) in human monocytic cell line, THP-1


10, 25, 100 g in poly bottle

Biochem/physiol Actions

Palmitic acid (PA) is a component of membrane phospholipids (PL) and adipose triacylglycerols (TAG). Elevated levels of palmitic acid contributes to the pathophysiology of atherosclerosis, type 2 diabetes mellitus, neurodegenerative diseases, obesity and cancer. PA promotes apoptosis in the endothelial cell by modulating the p38 mitogen-activated protein kinase (MAPK) pathway and favors expression of TNF-α and reactive oxygen species accumulation. PA promotes interleukin 8 (IL-8) synthesis in hepatocytes contributing to hepatic inflammation. PA by interacting with toll-like receptor 4 (TLR4) induces inflammatory injury in cardiomyoctes.
Palmitic acid is a straight-chain 16-carbon fatty acid. Diets rich in palmitic acid, along with lauric and myristic acids, are associated with increased serum levels of low-density lipoprotein cholesterol. Palmitic acid is the first fatty acid produced by lipogenesis. It is a negative regulator of acetyl-CoA carboxylase (ACC) and is implicated in fatty acid-induced insulin resistance.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves


NONH for all modes of transport

WGK Germany


Flash Point(F)

235.4 °F

Flash Point(C)

113 °C

Certificate of Analysis

Certificate of Origin

Biological and nutritional properties of palm oil and palmitic acid: effects on health
Mancini A, et al.
Molecules (Basel), 20(9), 17339-17361 (2015)
Palmitic acid induced vascular endothelial cell apoptosis contributes to the high severity of coronary artery disease in the Uygur population
Jiang H, et al.
Biomedical Research, 28(2), 17339-17361 (2017)
Palmitic acid: Physiological role, metabolism and nutritional implications
Carta G, et al.
Frontiers in Physiology, 8, 902-902 (2017)
Lipidomic Analysis of alpha Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment
Fanning S, et al.
Molecular Cell (2018)
Cangju Qinggan Jiangzhi Decoction Reduces the Development of NonAlcoholic Steatohepatitis and Activation of Kupffer Cells
Cheng Y, et al.
Cellular Physiology and Biochemistry, 48(3), 971-982 (2018)
Lipid Induced Insulin Resistance
Read More
Information on fatty acid synthesis and metabolism in cancer cells. Learn how proliferatively active cells require fatty acids for functions such as membrane generation, protein modification, and bioenergetic requirements. These fatty acids are derived either from dietary sources or are synthesized by the cell.
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