P5607

Sigma-Aldrich

L-Proline

from non-animal source, meets EP, USP testing specifications, suitable for cell culture

Synonym(s):
(S)-Pyrrolidine-2-carboxylic acid
Empirical Formula (Hill Notation):
C5H9NO2
CAS Number:
Molecular Weight:
115.13
Beilstein/REAXYS Number:
80810
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:

Quality Level

biological source

non-animal source

Agency/Method

meets EP testing specifications
meets USP testing specifications

assay

98.5-101.0% dry basis

form

powder

application(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white

mp

228 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL

Featured Industry

Pharmaceutical (small molecule)

SMILES string

OC(=O)[C@@H]1CCCN1

InChI

1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1

InChI key

ONIBWKKTOPOVIA-BYPYZUCNSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

L-proline has been used as a component of high-glucose-Dulbecco′s modified Eagle′s medium (HG-DMEM) for chondrocyte differentiation and for the culture of chondrocyte-like cells. It has also been used as a component of yeast nitrogen base for yeast cultures.

Packaging

25, 100 g in poly bottle
25 kg in poly drum
1 kg in poly bottle

Biochem/physiol Actions

Proline is a cyclic, non-essential, hydrophobic amino acid. It is a proteinogenic amino acid which is crucial for primary metabolism. In peptide chains, proline residues confer structural constraints and enhance the susceptibility of proximal peptide bonds to protease activity.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Alcohol-based quorum sensing plays a role in adhesion and sliding motility of the yeast Debaryomyces hansenii.
Gori K, et.al.
FEMS Yeast Research, 11(8), 643-652 (2011)
Link-N: The missing link towards intervertebral disc repair is species-specific
Frances C. Bach, et.al.
PLoS ONE, 12(11), 1-21 (2017)
TRP channels in brown and white adipogenesis from human progenitors: new therapeutic targets and the caveats associated with the common antibiotic, streptomycin
Anna Goralczyk
Faseb Journal, 2-18 (2017)
Proline: a multifunctional amino acid
La' szlo' Szabados and Arnould Savoure
Trends in Plant Science, 1-9 (2009)
Proline-Dependent Structural and Biological Properties of Peptides and Proteins
Arieh Yaron
Critical Reviews in Biochemistry and Molecular Biology, 28, 31-81 (2008)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.