P5884

Sigma-Aldrich

Brij® 58

average Mn ~1124

Synonym(s):
Polyoxyethylene (20) cetyl ether, Polyethylene glycol hexadecyl ether
Linear Formula:
HO(CH2CH2O)20C16H33
CAS Number:
Beilstein/REAXYS Number:
1899885
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

description

non-ionic

mol wt

micellar avg mol wt 79,000
average Mn ~1124

aggregation number

70

application(s)

protein quantification: suitable

CMC

0.08 mM (20-25°C)

mp

~38 °C

transition temp

cloud point >100 °C

HLB

16

SMILES string

CCCCCCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C56H114O21/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17-58-19-21-60-23-25-62-27-29-64-31-33-66-35-37-68-39-41-70-43-45-72-47-49-74-51-53-76-55-56-77-54-52-75-50-48-73-46-44-71-42-40-69-38-36-67-34-32-65-30-28-63-26-24-61-22-20-59-18-16-57/h57H,2-56H2,1H3

InChI key

NLMKTBGFQGKQEV-UHFFFAOYSA-N

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General description

Brij 58 is a nonionic surfactant or detergent for protein extraction and permeabilization of cells. It may be used in the preparation of yeast spheroplasts.

Application

Polyethylene glycol hexadecyl ether, or Brij 58, has been used in a study to assess properties of gemini-conventional surfactant mixtures and their effects on solubilization of polycyclic aromatic hydrocarbons. It has also been used in a study to investigate RNase-sensitive constraint of bacterial nucleoid structure.

Packaging

1 kg in poly bottle
100, 500 g in poly bottle

Legal Information

Brij is a registered trademark of Croda International PLC

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 2

Flash Point(F)

302.0 °F - closed cup

Flash Point(C)

150 °C - closed cup

M Kellermayer et al.
Journal of cellular physiology, 159(2), 197-204 (1994-05-01)
The plasma membrane of erythrocytes, as of other cells, is thought to act as the barrier responsible for maintaining intracellular gradients of most ions and small molecular species between the cell and its environment. Controlled application of the nonionic detergent...
Macromolecular crowding can account for RNase-sensitive constraint of bacterial nucleoid structure
Foley, P., et al
Biochemical and Biophysical Research Communications, 395, 6-6 (2010)
Study of surface and solution properties of gemini-conventional surfactant mixtures and their effects on solubilization of polycyclic aromatic hydrocarbons
Panda
Journal of Molecular Liquids, 163, 6-6 (2011)
Photodestruction of BDE-99 in micellar solutions of nonionic surfactants of Brij 35 and Brij 58
Li, X., et al.
Chemosphere, 78, 8-8 (2010)
Preparation of extracts from prokaryotes.
M Cull et al.
Methods in enzymology, 182, 147-153 (1990-01-01)
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