P7081

Sigma-Aldrich

1,2-Didecanoyl-sn-glycero-3-phosphocholine

≥99% (TLC)

Synonym(s):
Didecanoyllecithin, 3-sn-Phosphatidylcholine, 1,2-didecanoyl, (7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxodecyl)oxy]-3,5,9-trioxa-4-phosphanonadecan-1-aminium 4-oxide, inner salt, PC, PC(10:0/10:0), 1,2-Dicaprinoyl-sn-glycero-3-phosphocholine, L-α-Phosphatidylcholine, didecanoyl
Empirical Formula (Hill Notation):
C28H56NO8P
CAS Number:
Molecular Weight:
565.72
Beilstein/REAXYS Number:
3757665
MDL number:
PubChem Substance ID:

Quality Level

assay

≥99% (TLC)

form

powder

functional group

phospholipid

shipped in

ambient

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O)=O

InChI

1S/C28H56NO8P/c1-6-8-10-12-14-16-18-20-27(30)34-24-26(25-36-38(32,33)35-23-22-29(3,4)5)37-28(31)21-19-17-15-13-11-9-7-2/h26H,6-25H2,1-5H3/t26-/m1/s1

InChI key

MLKLDGSYMHFAOC-AREMUKBSSA-N

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Related Categories

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Studies on the complex formed between glucagon and dicaprylphosphatidylcholine.
J R Ernandes et al.
Biochimica et biophysica acta, 733(1), 75-86 (1983-08-24)
T Laursen et al.
The Annals of pharmacotherapy, 28(7-8), 845-848 (1994-07-01)
Current growth hormone (GH) therapy with daily subcutaneous injections results in elevated serum concentrations of GH lasting for several hours, whereas physiologic GH secretion is characterized by a short-duration peak and low basal concentrations. A closer imitation of this pattern...
S Carstens et al.
Diabetes, 42(7), 1032-1040 (1993-07-01)
To investigate the short-term effects of didecanoyl-L-alpha-phosphatidylcholine on the nasal mucosa and the mechanism by which didecanoyl-L-alpha-phosphatidylcholine enhances the nasal absorption of insulin, an in vitro model was developed. The mucosa from the posterior part of the rabbit nasal septum...
M A Unmack et al.
Pflugers Archiv : European journal of physiology, 434(3), 234-241 (1997-07-01)
The effects of mucosal application of the short-chain phospholipid didecanoyl-L-alpha-phosphatidylcholine (DDPC; with two saturated 10-carbon acyl chains) on active Na+ transport and transepithelial conductance (G) in the frog skin (Rana temporaria) were investigated. Active Na+ transport was measured as the...
J Y Legendre et al.
Biochemical and biophysical research communications, 217(1), 179-185 (1995-12-05)
Addition of short-chain phospholipids to the gramicidin S-DNA-dioleoyl phosphatidylethanolamine complex enhanced up to 6-fold beta-galactosidase expression in several cell-lines in vitro. Among the compounds tested, the most potent in enhancing transfection were the dicapryl- and the dicapryloyl phosphatidylcholine. In contrast...

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