P7127

Phospho(enol)pyruvic acid monopotassium salt

≥97% (enzymatic), powder

• Synonym(s): 2-(Phosphonooxy)-2-propenoic acid monopotassium salt, mono-Potassium phosphoenolpyruvate, PEP-K
• Empirical Formula (Hill Notation): C₃H₄KO₆P
• CAS Number: 4265-07-0
• Molecular Weight: 206.13
• Beilstein/REAXYS Number: 4603446
• EC Number: 224-247-0
• MDL number: MFCD00044476
• UNSPSC Code: 12352204
• PubChem Substance ID: 24898822
• NACRES: NA.32

Properties

• Product Name: Phospho(enol)pyruvic acid monopotassium salt, ≥97% (enzymatic)
• Quality Level: 200
• assay: ≥97% (enzymatic)
• form: powder
• solubility: water: 100 mg/mL, clear, colorless
• storage temp.: −20°C
• SMILES string: [K+].OC(=O)C(=C)OP(O)([O-])=O
• InChI: 1S/C3H5O6P.K/c1-2(3(4)5)9-10(6,7)8;/h1H2,(H,4,5)(H2,6,7,8);/q;+1/p-1
• InChI key: SOSDSEAIODNVPX-UHFFFAOYSA-M

Description

General description

Phospho(enol)pyruvic acid (PEP) acts as an inhibitor of hexokinase, phosphoglucose isomerase, phosphofructokinase and aldolase.[1] It is a bifunctional carbohydrate, which exhibits antioxidant property. PEP may be a potential organ preservation agent in clinical transplantation.[2]

Application

Phospho(enol)pyruvic acid monopotassium salt has been used:

• to maintain a constant concentration of adenosine triphosphate (ATP) for active gel assembly[3]
• as a component in assay buffer for in vitro ATPase assay[4]
• as a stock solution for optical trapping assay[5]

Biochem/physiol Actions

Phospho(enol)pyruvic acid (PEP) is involved in glycolysis and gluconeogeneis. In glycolysis, PEP is metabolized by Pyruvate Kinase to yield pyruvate. In plants, PEP is involved in the formation of aromatic amino acids as well as in the carbon fixation pathway.

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)