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P8129

Sigma-Aldrich

5β-Pregnan-3α-ol-20-one

Synonym(s):

3α-Hydroxy-5β-pregnan-20-one, 3α-Hydroxy-5β-tetrahydroprogesterone, Pregnanolone

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25 MG
$322.00

$322.00


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25 MG
$322.00

About This Item

Empirical Formula (Hill Notation):
C21H34O2
CAS Number:
Molecular Weight:
318.49
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77
Biological source:
synthetic (organic)
Form:
powder
Assay:
≥98% (TLC)

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$322.00


In StockDetails


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biological source

synthetic (organic)

Quality Level

assay

≥98% (TLC)

form

powder

solubility

chloroform: 50 mg/mL, clear, colorless

shipped in

ambient

Storage temp.

room temp

SMILES string

[H]C12CCC3C4CCC(C(C)=O)C4(C)CCC3C1(C)CC[C@H](O)C2

InChI

1S/C21H34O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14-19,23H,4-12H2,1-3H3

InChI key

AURFZBICLPNKBZ-UHFFFAOYSA-N

Gene Information

rat ... Gabra2(29706)

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This Item
M6013P9129D4000
biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

synthetic (organic)

assay

≥98% (TLC)

assay

≥98% (HPLC)

assay

≥98%

assay

≥99%

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

200

form

powder

form

powder

form

powder

form

crystalline powder

solubility

chloroform: 50 mg/mL, clear, colorless

solubility

chloroform: 50 mg/mL, clear, colorless to faintly yellow

solubility

ethanol: soluble 10 mg/mL, clear, colorless to faintly yellow

solubility

chloroform: 50 mg/mL, clear, colorless

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

Biochem/physiol Actions

5β-Pregnan-3α-ol-20-one or pregnanolone is a neurosteroid that acts as a positive allosteric modulator (PAMs) of γ-aminobutyric acid A receptors (GABAARs). It mediates anti-convulsive, anxiolytic and sedative effects.[1] Pregnanolone inhibits γ-aminobutyric acid C receptor (GABAC) receptor-based response and favors GABAA receptor-mediated currents.[2]

Pictograms

Health hazard

signalword

Warning

hcodes

pcodes

Hazard Classifications

Carc. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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