P8374

Sigma-Aldrich

Pyoverdines−Fe complex

from Pseudomonas fluorescens, >90% (HPLC)

Synonym(s):
Pyoverdines, Fe-Pv
NACRES:
NA.32

Quality Level

biological source

Pseudomonas fluorescens

assay

>90% (HPLC)

solubility

H2O: ~10 mg/mL

shipped in

wet ice

storage temp.

−20°C

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Application

Pyoverdines-Fe complex has been used in cyclic voltammetry to determine potential detection windows and peak potentials.

Biochem/physiol Actions

The complex ferri-pyoverdine acts as a signaling molecule inducing the production of secreted virulence factors in Pseudomonas aeruginosa. Ferri-pyoverdines promote the growth of both P. fluorescens and P. aeruginosa in minimal medium.
Pyoverdines, also called pseuobactins and pyoverdins, are fluorescent siderophores that have high affinity for iron (1032 M-1), and are synthesized by fluorescent pseudomonads under iron-deficient growth conditions. Pyoverdines were shown to prevent iron toxicity produced by iron overload in hepatocyte cultures and effectively scavenges the hydroxyl and peroxyl radicals. Pyoverdines are effective in acquiring iron from transferrin and lactoferrin. Pyoverdines are also involved in the suppression of pythium-induced damping-off of tomato and promotion of growth in some higher plants.

Physical form

Supplied as a mixture containing mainly the succinic acid (MW=1161), 2-hydroxy glutaramide (MW=1190), and succinamide (MW=1160) forms of pyoverdines, bound to iron.

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Electrochemical sensing of biomarker for diagnostics of bacteria-specific infections
Fatima A
Nanomedicine (London, England) (2016)
Fast Selective Detection of Pyocyanin Using Cyclic Voltammetry
Sensors (2016)
Paul A Beare et al.
Molecular microbiology, 47(1), 195-207 (2002-12-21)
Under iron-limiting conditions, Pseudomonas aeruginosa produces a siderophore called pyoverdine. Pyoverdine is secreted into the extracellular environment where it chelates iron, and the resulting ferri-pyoverdine complexes are transported back into the bacteria by a cell surface receptor protein FpvA. Pyoverdine...
Islem Gandouzi et al.
Materials (Basel, Switzerland), 12(7) (2019-04-14)
Pyoverdine is a fluorescent siderophore produced by Pseudomonas aeruginosa that can be considered as a detectable marker in nosocomial infections. The presence of pyoverdine in water can be directly linked to the presence of the P. aeruginosa, thus being a...

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