P8688
(S)-(−)-Propranolol hydrochloride
≥98% (TLC), powder
Synonym(s):
(S)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanol hydrochloride
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Quality Level
assay
≥98% (TLC)
form
powder
optical activity
[α]25/D −25.5°, c = 1.0 in ethanol(lit.)
mp
193-195 °C (lit.)
solubility
ethanol: 10 mg/mL
DMSO: <14.5 mg/mL
H2O: 50 mg/mL
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 8.0 mg/mL
originator
AstraZeneca
storage temp.
2-8°C
SMILES string
Cl[H].CC(C)NC[C@H](O)COc1cccc2ccccc12
InChI
1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H/t14-;/m0./s1
InChI key
ZMRUPTIKESYGQW-UQKRIMTDSA-N
Gene Information
human ... ADRB1(153), ADRB2(154), ADRB3(155), HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355)
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This Item | P0689 | P0884 | H127 |
---|---|---|---|
assay ≥98% (TLC) | assay ≥98% (TLC) | assay ≥99% (TLC) | assay ≥98% (HPLC) |
form powder | form - | form powder | form powder |
Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - |
solubility ethanol: 10 mg/mL, H2O: 50 mg/mL, DMSO: <14.5 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 8.0 mg/mL | solubility ethanol: 10 mg/mL, DMSO: <14.5 mg/mL, H2O: 50 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 8.0 mg/mL | solubility ethanol: 10 mg/mL, DMSO: <14.5 mg/mL, H2O: 50 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 8.0 mg/mL | solubility H2O: slightly soluble 1.5 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: >14 mg/mL, ethanol: soluble |
originator AstraZeneca | originator AstraZeneca | originator AstraZeneca | originator - |
General description
Application
Biochem/physiol Actions
Features and Benefits
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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