P9405

Sigma-Aldrich

O-Phospho-L-tyrosine

Synonym(s):
L-3-(4-Hydroxyphenyl)alanine 4′-phosphate, L-Tyrosine-O-phosphate
Empirical Formula (Hill Notation):
C9H12NO6P
CAS Number:
Molecular Weight:
261.17
Beilstein/REAXYS Number:
3150815
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

Quality Level

assay

≥95.0% (HPLC)

form

powder

application(s)

cell analysis: suitable

color

white to off-white

mp

225 °C

storage temp.

−20°C

SMILES string

N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(O)=O

InChI

1S/C9H12NO6P/c10-8(9(11)12)5-6-1-3-7(4-2-6)16-17(13,14)15/h1-4,8H,5,10H2,(H,11,12)(H2,13,14,15)/t8-/m0/s1

InChI key

DCWXELXMIBXGTH-QMMMGPOBSA-N

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Related Categories

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Simona Infantino et al.
Nature communications, 8(1), 891-891 (2017-10-14)
Arginine methylation catalyzed by protein arginine methyltransferases (PRMT) is a common post-translational modification in mammalian cells, regulating many important functions including cell signalling, proliferation and differentiation. Here we show the role of PRMT1 in B-cell activation and differentiation. PRMT1 expression...
Chi Hoon Park et al.
BMC cancer, 16, 35-35 (2016-01-24)
c-Met signaling has been implicated in oncogenesis especially in cells with c-met gene amplification. Since 20 % of gastric cancer patients show high level of c-Met expression, c-Met has been identified as a good candidate for targeted therapy in gastric cancer....
Julia Petschnigg et al.
Nature methods, 11(5), 585-592 (2014-03-25)
Cell signaling, one of key processes in both normal cellular function and disease, is coordinated by numerous interactions between membrane proteins that change in response to stimuli. We present a split ubiquitin-based method for detection of integral membrane protein-protein interactions...
Jesse J Balic et al.
Cytokine, 92, 118-123 (2017-02-06)
Deregulated gp130-dependent STAT3 signalling by the pleiotropic cytokine interleukin (IL)-11 has been implicated in the pathogenesis of gastric cancer (GC), the third most common cancer worldwide. While the IL-11-gp130-STAT3 signalling axis has traditionally been thought to exclusively use the membrane-bound...
Bidur Paudel et al.
Biology of reproduction, 100(2), 440-454 (2018-09-22)
Mammalian sperm undergo a series of biochemical and physiological changes collectively known as capacitation in order to acquire the ability to fertilize. Although the increase in phosphorylation associated with mouse sperm capacitation is well established, the identity of the proteins...

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