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P9528

Sigma-Aldrich

Polyuridylic acid potassium salt

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Synonym(s):
Poly(U) potassium salt
CAS Number:
MDL number:
NACRES:
NA.51

Assay

≥98% (TLC)

Quality Level

form

lyophilized powder

solubility

water: 19.60-20.40 mg/mL, clear to slightly hazy, colorless

storage temp.

−20°C

InChI

1S/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1

InChI key

DJJCXFVJDGTHFX-XVFCMESISA-N

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1 of 4

This Item
P4154P4404K2000
form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

powder

solubility

water: 19.60-20.40 mg/mL, clear to slightly hazy, colorless

solubility

water: 4.80-5.20 mg/mL, clear to hazy, colorless to faintly yellow

solubility

water: 19.60-20.40 mg/mL, clear to slightly hazy, colorless to light yellow

solubility

water: 100 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

-

Application

Polyuridylic acid (Poly(U)), a homopolymer of uridine, is used as a single-stranded RNA model compound often in comparison with other ssRNA model oligonucleotides such as Poly(I) and Poly(C) to study processes that are dependent upon ssRNA regulation such as Toll-like receptor regulation. Poly(U) is used as an effective agonist for TLR7.

Preparation Note

Prepared from UDP using polynucleotide phosphorylase.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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