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PHG0021

SAFC

Choline chloride

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Synonym(s):
(2-Hydroxyethyl)trimethylammonium chloride
Linear Formula:
(CH3)3N(Cl)CH2CH2OH
CAS Number:
Molecular Weight:
139.62
Beilstein:
3563126
EC Number:
MDL number:
NACRES:
NA.21

biological source

synthetic

Quality Level

form

powder

mol wt

Mw 139.62 g/mol

technique(s)

cell culture | mammalian: suitable

impurities

Endotoxin, microbial and lead, tested

color

white

pH

5.0-6.5 (25 °C, 140 g/L)

mp

302-305 °C (dec.) (lit.)

solubility

water: soluble 140 g/L

suitability

suitable for (manufacturing use)

foreign activity

foreign activity (Cytotoxicity; tested)

SMILES string

[Cl-].C[N+](C)(C)CCO

InChI

1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1

InChI key

SGMZJAMFUVOLNK-UHFFFAOYSA-M

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This Item
S1702G5792C5735
Choline chloride

SAFC

PHG0021

Choline chloride

Sodium cholate hydrate

SAFC

S1702

Sodium cholate hydrate

L-Glutamine

SAFC

G5792

L-Glutamine

L-Cystine

SAFC

C5735

L-Cystine

mol wt

Mw 139.62 g/mol

mol wt

micellar avg mol wt 900-1300

mol wt

-

mol wt

-

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

color

white

color

-

color

-

color

-

solubility

water: soluble 140 g/L

solubility

-

solubility

H2O: 25 mg/mL

solubility

1 M HCl: 100 mg/mL

Quality Level

400

Quality Level

400

Quality Level

400

Quality Level

400

General description

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
To request the documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to documentation for this product requires a confidentiality disclosure agreement.

Biochem/physiol Actions

The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes .

Substrates

Choline acetyltransferase substrate

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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