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Anti-TLR4 antibody produced in rabbit

Name: Anti-TLR4 antibody produced in rabbit
Brand: SIGMA
Price: 529 USD

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-Toll-like receptor 4

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Pack Size	SKU	Availability	Price
100 μg		Check Cart for Availability	$529.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD03455299

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA (i), ICC, IF, IHC, WB

Citations:

$529.00

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Properties

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

predicted mol wt 92 kDa

species reactivity

human

technique(s)

immunocytochemistry: suitable, immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable

UniProt accession no.

O00206

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TLR4(7099)

Description

General description

Toll-like receptors (TLRs) are transmembrane receptors expressed on the surface of immune and non-immune cells. There are at least 13 different TLRs identified that mediate signalling pathways contributing to acute inflammatory processes during tissue damage and bacterial infections TLR2 is highly inducible by numerous inflammatory mediators resulting in translocation of transcription factor NF-κB-mediated proinflammatory cytokines and immune responses

Immunogen

a peptide corresponding to 15 amino acids near the amino-terminus of human TLR4.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3141.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Show Differences

1 of 1

This Item	HPA049174	PRS3135	SAB3500313
Sigma-Aldrich PRS3141 Anti-TLR4 antibody produced in rabbit	Sigma-Aldrich HPA049174 Anti-TLR4 antibody produced in rabbit	Sigma-Aldrich PRS3135 Anti-TLR2 antibody produced in rabbit	Sigma-Aldrich SAB3500313 Anti-TLR9 antibody produced in rabbit
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
Gene Information human ... TLR4(7099)	Gene Information human ... TLR4(7099)	Gene Information human ... TLR2(7097)	Gene Information human ... TLR9(54106)
mol wt predicted mol wt 92 kDa	mol wt -	mol wt -	mol wt -

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

31410303

3141-0303

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Toll-like Receptor 4 Modulation as a Strategy to Treat Sepsis

Wittebole X et al

Mediators of Inflammation, doi: 10-doi: 10 (2010)

Toll-like receptors 2 and 4: initiators of non-septic inflammation in critical care medicine?

Emmanuel Lorne et al.

Intensive care medicine, 36(11), 1826-1835 (2010-08-07)

Although the role of Toll-like receptors (TLRs) in bacterial infection and sepsis is well characterized, recent studies have also shown that TLR4 and TLR2 can play an important role in contributing to acute inflammatory processes and organ dysfunction in settings

Role of TLR- / NLR-signaling and the associated cytokines involved in recruitment of neutrophils in murine models of Staphylococcus aureus infection.

Shneh Sethi et al.

Virulence, 2(4), 316-328 (2011-07-16)

Recent studies in murine models of Staphylococcus aureus (S. aureus) infection have investigated the association of Toll-like receptor (TLR)2, TLR4, myeloid differentiation factor 88 (MyD88) and Nod-like receptor (NOD)2 with the production of cytokines / chemokines and their involvement in

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Global Trade Item Number

SKU	GTIN
SBP3141-0.05MG	04061832165974
PRS3141-100UG	04061836687038

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