PRS3613

Sigma-Aldrich

Anti-Beclin-1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):
Anti-Beclin 1, autophagy related, Anti-Coiled-coil myosin-like Bcl-2-interacting protein
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, rat, human

application(s)

ELISA: suitable
immunocytochemistry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
western blot: suitable

conjugate

unconjugated

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... BECN1(8678)

Immunogen

a 17 amino acid peptide from near the amino-terminus of human Beclin-1.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3613.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

RIDADR

NONH for all modes of transport

WGK Germany

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Peter Sykora et al.
Nucleic acids research, 43(2), 943-959 (2015-01-02)
We explore the role of DNA damage processing in the progression of cognitive decline by creating a new mouse model. The new model is a cross of a common Alzheimer's disease (AD) mouse (3xTgAD), with a mouse that is heterozygous...
Willem-Jan M Schellekens et al.
Critical care (London, England), 18(1), R28-R28 (2014-02-11)
Diaphragm weakness induced by prolonged mechanical ventilation may contribute to difficult weaning from the ventilator. Hypercapnia is an accepted side effect of low tidal volume mechanical ventilation, but the effects of hypercapnia on respiratory muscle function are largely unknown. The...
Yalan Huang et al.
Frontiers in physiology, 10, 606-606 (2019-06-14)
Severe burn injury induces intestinal barrier dysfunction; however, the underlying mechanisms remain elusive. Our previous studies have shown that the intestinal epithelial tight junction (TJ) barrier dysfunction is associated with both endoplasmic reticulum (ER) stress and autophagy in severely burned...
Cynthia de la Fuente et al.
PloS one, 13(2), e0191983-e0191983 (2018-02-07)
Rift Valley fever virus (RVFV) infects both ruminants and humans leading to a wide variance of pathologies dependent on host background and age. Utilizing a targeted reverse phase protein array (RPPA) to define changes in signaling cascades after in vitro...
Cristian Gerónimo-Olvera et al.
Cell death & disease, 8(6), e2911-e2911 (2017-07-01)
Autophagy is triggered during nutrient and energy deprivation in a variety of cells as a homeostatic response to metabolic stress. In the CNS, deficient autophagy has been implicated in neurodegenerative diseases and ischemic brain injury. However, its role in hypoglycemic...

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