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PVP360

Sigma-Aldrich

Polyvinylpyrrolidone

mol wt (number average molecular weight Mn 360kDa)

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Synonym(s):
PVP, Polyvidone, Povidone
Linear Formula:
(C6H9NO)n
CAS Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

biological source

synthetic

Quality Level

form

powder

mol wt

(number average molecular weight Mn 360kDa)

viscosity number

80-100(lit.)

solubility

water: soluble 100 mg/mL

cation traces

heavy metals (as Pb): ≤5 ppm

SMILES string

C=CN1CCCC1=O
C=CN1CCCC1=O

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

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General description

Polyvinyl pyrrolidone [poly(N-vinyl-2-pyrrolidone), PVP] is a stable, bulky, non-toxic, non-ionic polymer widely used in medical, industrial, pharmaceutical, food, cosmetic, and electronic applications. It can be prepared from N-vinyl-2-pyrrolidone by free radical polymerization.

Application

PVP can be used as:
  • A stabilizer in the synthesis of metallic nanoparticles (NPs) as it avoids the aggregation of NPs via repulsive forces produced by its hydrophobic carbon chains.
  • A capping agent in the synthesis of rodlike hydroxyapatite (HAp) nanoparticles to control the nucleation and growth of HAp crystal.
  • A synthetic polymer vehicle in the pharmaceutical industry for dispersing and suspending drugs.
  • An emulsifier and disintegrant for solution polymerization.

Other Notes

Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Analía I Alet et al.
Clinical hemorheology and microcirculation, 64(2), 157-165 (2016-03-24)
Drugs used during anesthesia might induce disturbance on microcirculation due to their systemic cardiovascular actions and to direct hemorheological effects. A comparative investigation of the hemorheological alterations related to in vitro propofol treatment of red blood cells (RBCs) from healthy
Gili Dardikman-Yoffe et al.
Science advances, 6(15), eaay7619-eaay7619 (2020-04-18)
We present a new acquisition method that enables high-resolution, fine-detail full reconstruction of the three-dimensional movement and structure of individual human sperm cells swimming freely. We achieve both retrieval of the three-dimensional refractive-index profile of the sperm head, revealing its
Zhang Y and L Jinjun
Crystal Growth & Design, 8(7), 2101-2107 (2008)
The Structural and Optical Characteristics of Polyvinylpyrrolidone Doped with Nano crystal NaF Films
Mustafa FA
Academic Press Dictionary of Science and Technology, 4(3), 125-125 (2013)
Physicochemical Characterization of Polyvinyl Pyrrolidone: A Tale of Two Polyvinyl Pyrrolidones
Mireles LK, et al.
ACS Omega, 5(47), 30461-30467 (2020)

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