All Photos(4)

PVP360

Sigma-Aldrich

Polyvinylpyrrolidone

mol wt (number average molecular weight Mn 360)

Synonym(s):
PVP, Povidone, Polyvidone
Linear Formula:
(C6H9NO)n
CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

form

powder

Quality Level

mol wt

(number average molecular weight Mn 360)

viscosity number

80-100(lit.)

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

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General description

Polyvinyl pyrrolidone [poly(N-vinyl-2-pyrrolidone), PVP] is a stable, bulky, non-toxic, non-ionic polymer widely used in medical, industrial, pharmaceutical, food, cosmetic, and electronic applications. It can be prepared from N-vinyl-2-pyrrolidone by free radical polymerization.

Application

PVP can be used as:
  • A stabilizer in the synthesis of metallic nanoparticles (NPs) as it avoids the aggregation of NPs via repulsive forces produced by its hydrophobic carbon chains.
  • A capping agent in the synthesis of rodlike hydroxyapatite (HAp) nanoparticles to control the nucleation and growth of HAp crystal.
  • A synthetic polymer vehicle in the pharmaceutical industry for dispersing and suspending drugs.
  • An emulsifier and disintegrant for solution polymerization.

Packaging

1, 5 kg in poly drum
100, 500 g in poly bottle

Other Notes

Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.

Storage Class Code

11 - Combustible Solids

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Gili Dardikman-Yoffe et al.
Science advances, 6(15), eaay7619-eaay7619 (2020-04-18)
We present a new acquisition method that enables high-resolution, fine-detail full reconstruction of the three-dimensional movement and structure of individual human sperm cells swimming freely. We achieve both retrieval of the three-dimensional refractive-index profile of the sperm head, revealing its...
Comparison of static and dynamic sonication as process intensification for particle size reduction using a factorial design
Bartos C, et al.
Chemical Engineering and Processing, 87, 26-34 (2015)
Physicochemical Characterization of Polyvinyl Pyrrolidone: A Tale of Two Polyvinyl Pyrrolidones
Mireles LK, et al.
ACS Omega, 5(47), 30461-30467 (2020)
Analía I Alet et al.
Clinical hemorheology and microcirculation, 64(2), 157-165 (2016-03-24)
Drugs used during anesthesia might induce disturbance on microcirculation due to their systemic cardiovascular actions and to direct hemorheological effects. A comparative investigation of the hemorheological alterations related to in vitro propofol treatment of red blood cells (RBCs) from healthy...
Wantao Li et al.
Frontiers in cell and developmental biology, 8, 265-265 (2020-07-17)
Gushukang (GSK) is a traditional herbal compound used in Chinese medicine for the treatment of osteoporosis. Numerous studies have been conducted to elucidate the effects of GSK, but the mechanisms underlying these effects remain unclear. In the present study, we...

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