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PVP360

Sigma-Aldrich

Polyvinylpyrrolidone

powder, average molecular weight Mn 360kDa

Synonym(s):

PVP, Polyvidone, Povidone

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About This Item

Linear Formula:
(C6H9NO)n
CAS Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

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Product Name

Polyvinylpyrrolidone, mol wt (number average molecular weight Mn 360kDa)

biological source

synthetic

Quality Level

form

powder

mol wt

(number average molecular weight Mn 360kDa)

viscosity number

80-100(lit.)

solubility

water: soluble 100 mg/mL

cation traces

heavy metals (as Pb): ≤5 ppm

SMILES string

C=CN1CCCC1=O
C=CN1CCCC1=O

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

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1 of 4

This Item
P5288P23075295
form

powder

form

powder

form

powder

form

solid

cation traces

heavy metals (as Pb): ≤5 ppm

cation traces

-

cation traces

-

cation traces

heavy metals: ≤10 ppm

solubility

water: soluble 100 mg/mL

solubility

-

solubility

-

solubility

water: 20%

biological source

synthetic

biological source

-

biological source

-

biological source

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

mol wt

(number average molecular weight Mn 360kDa)

mol wt

360,000

mol wt

average mol wt 10,000

mol wt

-

General description

Polyvinyl pyrrolidone [poly(N-vinyl-2-pyrrolidone), PVP] is a stable, bulky, non-toxic, non-ionic polymer widely used in medical, industrial, pharmaceutical, food, cosmetic, and electronic applications. It can be prepared from N-vinyl-2-pyrrolidone by free radical polymerization.[1][2]

Application

PVP can be used as:
  • A stabilizer in the synthesis of metallic nanoparticles (NPs) as it avoids the aggregation of NPs via repulsive forces produced by its hydrophobic carbon chains.[1][2]
  • A capping agent in the synthesis of rodlike hydroxyapatite (HAp) nanoparticles to control the nucleation and growth of HAp crystal.[3]
  • A synthetic polymer vehicle in the pharmaceutical industry for dispersing and suspending drugs.[4]
  • An emulsifier and disintegrant for solution polymerization.[5]

Other Notes

Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Physicochemical Characterization of Polyvinyl Pyrrolidone: A Tale of Two Polyvinyl Pyrrolidones
Mireles LK, et al.
ACS Omega, 5(47), 30461-30467 (2020)
Comparison of static and dynamic sonication as process intensification for particle size reduction using a factorial design
Bartos C, et al.
Chemical Engineering and Processing, 87, 26-34 (2015)
Gili Dardikman-Yoffe et al.
Science advances, 6(15), eaay7619-eaay7619 (2020-04-18)
We present a new acquisition method that enables high-resolution, fine-detail full reconstruction of the three-dimensional movement and structure of individual human sperm cells swimming freely. We achieve both retrieval of the three-dimensional refractive-index profile of the sperm head, revealing its
Analía I Alet et al.
Clinical hemorheology and microcirculation, 64(2), 157-165 (2016-03-24)
Drugs used during anesthesia might induce disturbance on microcirculation due to their systemic cardiovascular actions and to direct hemorheological effects. A comparative investigation of the hemorheological alterations related to in vitro propofol treatment of red blood cells (RBCs) from healthy
Wantao Li et al.
Frontiers in cell and developmental biology, 8, 265-265 (2020-07-17)
Gushukang (GSK) is a traditional herbal compound used in Chinese medicine for the treatment of osteoporosis. Numerous studies have been conducted to elucidate the effects of GSK, but the mechanisms underlying these effects remain unclear. In the present study, we

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

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    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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