MilliporeSigma
All Photos(1)

Documents

PZ0036

Sigma-Aldrich

Rucaparib camsylate

≥98% (HPLC)

Sign Into View Organizational & Contract Pricing

Synonym(s):
8-fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-Pyrrolo[4,3,2-ef][2]benzazepin-6-one camsylate
Empirical Formula (Hill Notation):
C19H18FN3O · C10H16O4S
CAS Number:
Molecular Weight:
555.66
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

color

pale yellow

solubility

DMSO: 2 mg/mL, clear

shipped in

dry ice

storage temp.

−20°C

SMILES string

FC1=CC(C(NCC2)=O)=C3C2=C(C4=CC=C(CNC)C=C4)NC3=C1.CC5(C)[C@@H]6CC[C@@]5(CS(O)(=O)=O)C(C6)=O

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
PZ0380C191SML2213
Rucaparib camsylate ≥98% (HPLC)

Sigma-Aldrich

PZ0036

Rucaparib camsylate

PF-04447943 ≥98% (HPLC)

Sigma-Aldrich

PZ0380

PF-04447943

Capsazepine ≥98% (HPLC), solid

Sigma-Aldrich

C191

Capsazepine

CPI-637 ≥98% (HPLC)

Sigma-Aldrich

SML2213

CPI-637

form

powder

form

powder

form

solid

form

powder

color

pale yellow

color

white to beige

color

off-white

color

white to beige

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: >10 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

shipped in

dry ice

shipped in

-

shipped in

-

shipped in

-

storage temp.

−20°C

storage temp.

room temp

storage temp.

2-8°C

storage temp.

−20°C

Biochem/physiol Actions

Rucaparib is an inhibitor of the DNA repair enzyme poly-ADP ribose polymerase-1 (PARP-1). It has been found to have anticancer activity in a number of cancers and has been approved for treatment of previously treated, BRCA-mutant ovarian cancer.

Pictograms

Health hazard

Signal Word

Warning

Hazard Statements

Hazard Classifications

Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 2

1 of 2

Yaroslava Karpova et al.
Biochemical pharmacology, 167, 149-162 (2019-03-19)
In our previous studies of the molecular mechanisms of poly(ADP-ribose) polymerase 1 (PARP-1)-mediated transcriptional regulation we identified a novel class of PARP-1 inhibitors targeting the histone-dependent route of PARP-1 activation. Because histone-dependent activation is unique to PARP-1, non-NAD-like PARP-1 inhibitors

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service