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PZ0100

Sigma-Aldrich

CP-154526 hydrochloride

≥98% (HPLC)

Synonym(s):
N-Butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine monohydrochloride
Empirical Formula (Hill Notation):
C23H32N4 · HCl
CAS Number:
Molecular Weight:
400.99
MDL number:
PubChem Substance ID:
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

manufacturer/tradename

Pfizer®

color

white to beige

solubility

DMSO: 10 mg/mL, clear

originator

Pfizer

storage temp.

2-8°C

SMILES string

Cl.CCCCN(CC)c1nc(C)nc2n(cc(C)c12)-c3c(C)cc(C)cc3C

InChI

1S/C23H32N4.ClH/c1-8-10-11-26(9-2)22-20-18(6)14-27(23(20)25-19(7)24-22)21-16(4)12-15(3)13-17(21)5;/h12-14H,8-11H2,1-7H3;1H

InChI key

ZWDLBNCJWNENFF-UHFFFAOYSA-N

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PZ0264PZ0362SML0588
assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥95% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

manufacturer/tradename

Pfizer®

manufacturer/tradename

Pfizer®

manufacturer/tradename

Pfizer®

manufacturer/tradename

-

color

white to beige

color

white to beige

color

white to beige

color

white to beige

solubility

DMSO: 10 mg/mL, clear

solubility

DMSO: 5 mg/mL, clear (warmed)

solubility

H2O: 2 mg/mL, clear (warmed)

solubility

H2O: 15 mg/mL, clear

originator

Pfizer

originator

Pfizer

originator

Pfizer

originator

-

Biochem/physiol Actions

CP-154526 is a selective, non-peptide antagonist of corticotropin releasing factor receptors (CRF1).

Features and Benefits

This compound is featured on the Corticotropin-Releasing Factor Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Other Notes

This compound was developed by Pfizer for Cytokines & Growth Factors research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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