PZ0112

PD-184161

≥98% (HPLC)

• Synonym(s): 5-Bromo-2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluoro-benzamide, PF-1529483, PF-3011370, UK-287074
• Empirical Formula (Hill Notation): C₁₇H₁₃BrClF₂IN₂O₂
• CAS Number: 212631-67-9
• Molecular Weight: 557.56
• MDL number: MFCD16038897
• PubChem Substance ID: 329823704

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• manufacturer/tradename: Pfizer^®
• color: white to off-white
• solubility: DMSO: >10 mg/mL
• originator: Pfizer
• storage temp.: 2-8°C
• SMILES string: Fc1c(F)c(Nc2ccc(I)cc2Cl)c(cc1Br)C(=O)NOCC3CC3
• InChI: 1S/C17H13BrClF2IN2O2/c18-11-6-10(17(25)24-26-7-8-1-2-8)16(15(21)14(11)20)23-13-4-3-9(22)5-12(13)19/h3-6,8,23H,1-2,7H2,(H,24,25)
• InChI key: VJNZMSLGVUSPCF-UHFFFAOYSA-N

Description

Biochem/physiol Actions

PD-184161 is a MEK inhibitor.

Features and Benefits

This compound is featured on the MAPKKKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Other Notes

This compound was developed by Pfizer for Kinase Phosphatase Biology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

Sold for research purposes under agreement from Pfizer Inc.

Pfizer is a registered trademark of Pfizer, Inc.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable