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Retinyl palmitate

Name: Retinyl palmitate
Brand: SIGMA
Price: 77.7 USD
Availability: InStock

potency: ≥1,700,000 USP units per g

Synonym(s):

Vitamin A palmitate, all−trans−Retinol palmitate

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Size/SKU	Availability	Price
5 g	Available to ship TODAYfromMILWAUKEE	$77.70

About This Item

Empirical Formula (Hill Notation):

C₃₆H₆₀O₂

CAS Number:

79-81-2

Molecular Weight:

524.86

UNSPSC Code:

12352205

NACRES:

NA.79

PubChem Substance ID:

24899347

EC Number:

201-228-5

Beilstein/REAXYS Number:

1917366

MDL number:

MFCD00019414

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Properties

biological source

synthetic (organic)

Quality Segment

200

form

solid or viscous liquid

potency

≥1,700,000 USP units per g

does not contain

antioxidant

color

yellow to yellow-green

mp

26 °C

storage temp.

2-8°C

SMILES string

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(CCCCCCCCCCCCCCC)=O)C(C)(C)CCC1

InChI

1S/C36H60O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-25-35(37)38-30-28-32(3)23-20-22-31(2)26-27-34-33(4)24-21-29-36(34,5)6/h20,22-23,26-28H,7-19,21,24-25,29-30H2,1-6H3/b23-20+,27-26+,31-22+,32-28+

InChI key

VYGQUTWHTHXGQB-FFHKNEKCSA-N

Description

General description

Retinyl palmitate or vitamin A palmitate is a retinoid, which is an acid form of vitamin A. Retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain. Retinyl palmitate is a major storage form of vitamin A found in epidermis. Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as needed.

Application

Retinyl palmitate has been used as a standard in high performance liquid chromatography (HPLC).[1] It has also been used to study its effect on brain regeneration in larval Xenopus laevis.

Biochem/physiol Actions

Review: Vitamin A metabolism.

Retinyl palmitate is widely used in pharmaceutical applications. It is also extensively used in cosmetic formulations due to its beneficial effects on the appearance of skin and anti-oxidant properties. Retinyl palmitate acts as a teratogen and affect vertebrate embryogenesis and regeneration. It is added as a source of vitamin A in low fat and skim milks. Retinyl palmitate acts as a chemopreventive or antineoplastic agent.

Packaging

Sealed ampule.

Physical form

oil or solid

Compare Similar Items

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Show Differences

1 of 1

This Item	R3375	1602502	PHR1235
Sigma-Aldrich R1512 Retinyl palmitate	Sigma-Aldrich R3375 Retinyl palmitate	USP 1602502 Retinyl palmitate	Supelco PHR1235 Retinyl Palmitate (Vitamin A Palmitate)
biological source synthetic (organic)	biological source synthetic (organic)	biological source -	biological source -
form solid or viscous liquid	form oil	form -	form -
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C
mp 26 °C	mp 26 °C	mp -	mp -
color yellow to yellow-green	color yellow to orange	color -	color -
does not contain antioxidant	does not contain -	does not contain -	does not contain -

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pictograms

GHS08

signalword

Danger

hcodes

H360D,H412

pcodes

P202 - P273 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Aquatic Chronic 3 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

No data available

flash_point_c

No data available

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Questions

3 years ago

What is the difference in purity and melting point among Retinyl palmitate PHR1235, R3375 and R1512?

1 answer
1. Technical Support
  
  2 years ago
  
  The melting point of Retinyl palmitate is very close to room temperature, about 25-30°C. However, melting point is not part of the Quality Control (QC) specifications for any of the Retinyl palmitate products listed.
  The differences in purity testing for each is as follows:
  Product R1512 is assayed for potency in USP units per gram, but not purity. The minimum activity is 1.7M units per gram.
  Product R3375 is assayed for both potency in USP units per gram and purity by HPLC. The average activity is 1.8M units per gram. The minimum purity is 90%.
  Product PHR1235 is a Certified Reference Material (CRM) that is traceable to the USP primary standard and assayed for both potency in USP units per gram and purity by HPLC. Values are reported on a lot specific basis as compared to the current USP primary standard 1602502.
  
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