RU 26752

≥98% (HPLC), solid

17α-Hydroxy-3-oxo-7α-propylpregn-4-ene-21-carboxylic acid γ-lactone
Empirical Formula (Hill Notation):
CAS Number:
Molecular Weight:
MDL number:
PubChem Substance ID:
Pricing and availability is not currently available.

Quality Level


≥98% (HPLC)




DMSO: soluble 20 mg/mL at 60 °C (warming up for 20 minutes)

storage temp.


SMILES string




InChI key



10, 25, 100 mg in glass bottle

Biochem/physiol Actions

RU 26752 is a mineralocorticoid receptor antagonist.


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Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes


Risk Statement



NONH for all modes of transport

WGK Germany


C B Whorwood et al.
Endocrinology, 135(3), 901-910 (1994-09-01)
The induction of Na,K-ATPase plays a vital role in mediating epithelial sodium transport. Although its activity is regulated by corticosteroids, it is uncertain whether this is predominantly by mineralo- or glucocorticoid mechanisms. 11 beta-Hydroxysteroid dehydrogenase (11 beta HSD) catalyzes the...
M Mirshahi et al.
Biochemical and biophysical research communications, 219(1), 150-156 (1996-02-06)
Immunoblotting with a polyclonal antibody, directed against the mineralocorticoid receptor protein purified from rat kidney in presence of the receptor-specific ligand RU 26752, labeled a single 98-102 kDa band in soluble extracts from bovine retina and from cultured bovine retinal...
K Ben Rhouma et al.
Archives of physiology and biochemistry, 105(2), 216-224 (1997-04-01)
The thymolytic action of dexamethasone (DEXA) and aldosterone (ALDO) has been studied in vitro and in vivo. In vitro, in the presence of DEXA, the number of apoptotic cells increased with time. After 6 hours of incubation, 55 and 86%...
L Jacobson et al.
Brain research, 625(1), 84-92 (1993-10-15)
It is unclear whether in vitro corticosteroid receptor binding assays have used inappropriately high concentrations of synthetic corticosteroid competitors, thereby potentially introducing error into estimates of type I (mineralocorticoid) and type II (glucocorticoid) receptor binding. To determine more accurately the...
M Mirshahi et al.
Neuroendocrinology, 65(1), 70-78 (1997-01-01)
We studied the presence of the mineralocorticoid receptor (MCR) in the eye with the aid of a number of immunochemical techniques. Immunoblotting with a polyclonal antibody, directed against the rat renal MCR, revealed a single band of about 102 kD...

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