R9400

Monoclonal Anti-RANTES antibody produced in rat

clone 53405.111, purified immunoglobulin, lyophilized powder

• Synonym(s): Anti-D17S136E, Anti-RANTES, Anti-SCYA5, Anti-SIS-delta, Anti-SISd, Anti-TCP228, Anti-eoCP
• MDL number: MFCD01635727
• NACRES: NA.41

Properties

• biological source: rat
• Quality Level: 100
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 53405.111, monoclonal
• form: lyophilized powder
• purified by: using protein G
• species reactivity: mouse
• technique(s): immunocytochemistry: 8-25 μg/mL using mouse splenocytes; neutralization: suitable
• isotype: IgG2a
• UniProt accession no.: P30882
• storage temp.: −20°C
• Gene Information: mouse ... Ccl5(20304)

Description

Immunogen

purified, E. coli-derived, recombinant mouse RANTES.

Packaging

500 μg

Biochem/physiol Actions

RANTES (Regulated upon Activation, Normal T cell Expressed and Secreted; CCL5) is a chemokine that brings T cells, monocytes, eosinophils, NK cells, dendritic cells and mast cells to the site of infection or inflammation. RANTES has an unusual kinetic profile and is secreted 3-5 days after the activation of the T cells. It also exhibits antimicrobial activity by inducing the production of nitric oxide in macrophages. The expression of RANTES is regulated mainly by JAK/STAT and NF-κB pathways.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose pH 7.4.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable