Skip to Content
MilliporeSigma

RAB0441

Phospho-Stat1 (pSer727) and pan-Stat1 ELISA Kit

for detection of phospho-stat1 (pSer727) and pan-stat1 in human or mouse cell and tissue lysates

Slide 1 of 1
Sign In to View Organizational & Contract Pricing.

Select a Size

1 KIT

$839.00

$839.00

Usually ships in 1 week. (Orders outside of US and Europe, please allow an additional 1-2 weeks for delivery)

About This Item

NACRES:
NA.32
UNSPSC Code:
41116158

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Phospho-Stat1 (pSer727) and pan-Stat1 ELISA Kit, for detection of phospho-stat1 (pSer727) and pan-stat1 in human or mouse cell and tissue lysates

species reactivity

mouse, human

technique(s)

ELISA: suitable
capture ELISA: suitable

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... STAT1(6772)
mouse ... STAT1(20846)

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
RAB0443RAB0446RAB0454
Phospho-Stat1 (pSer727) and pan-Stat1 ELISA Kit for detection of phospho-stat1 (pSer727) and pan-stat1 in human or mouse cell and tissue lysates

Sigma-Aldrich

RAB0441

Phospho-Stat1 (pSer727) and pan-Stat1 ELISA Kit

Phospho-Stat1 (pTyr701) and pan-Stat1 ELISA Kit for detection of phospho-stat1 (pTyr701) and pan-stat1 in human or mouse cell and tissue lysates

Sigma-Aldrich

RAB0443

Phospho-Stat1 (pTyr701) and pan-Stat1 ELISA Kit

Phospho-Stat3 (pTyr705) ELISA Kit for detection of phospho-stat3 (pTyr705) in human, mouse or rat cell and tissue lysates

Sigma-Aldrich

RAB0446

Phospho-Stat3 (pTyr705) ELISA Kit

Cell-Based phospho-STAT ELISA Samper Kit for detecting phospho-STAT1 (pTyr701), phospho-STAT3 (pTyr705), and phospho-STAT5 (pTyr694) in cultured cell lines 192 assays

Sigma-Aldrich

RAB0454

Cell-Based phospho-STAT ELISA Samper Kit for detecting phospho-STAT1 (pTyr701), phospho-STAT3 (pTyr705), and phospho-STAT5 (pTyr694) in cultured cell lines

Gene Information

human ... STAT1(6772)
mouse ... STAT1(20846)

Gene Information

human ... STAT1(6772)
mouse ... STAT1(20846)

Gene Information

human ... STAT3(6774)
mouse ... STAT3(20848)
rat ... STAT3(25125)

Gene Information

human ... STAT6(6778)
mouse ... STAT6(20852)
rat ... STAT6(362896)

species reactivity

mouse, human

species reactivity

mouse, human

species reactivity

human, mouse, rat

species reactivity

rat, human, mouse

technique(s)

ELISA: suitable, capture ELISA: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Signal transducer and activator of transcription 1 (STAT1) undergoes phosphorylation on serine-727. This Phospho-Stat1 regulates pro- and anti-apoptotic genes following several stress-induced responses. STAT-1 interacts with p53 and promotes p53-mediated transcriptional gene activity and apoptosis. STAT-1 is an essential factor of stress-induced and DNA damage-induced checkpoint pathways and thus, acts as a tumour suppressor. STAT-1 functions as a pro-apoptotic factor in cardiac myocytes, brain or liver exposed to ischaemia–reperfusion injury.[1] Thus, inhibition of STAT-1-activated pathway by epigallocatechin-3-gallate (EGCG), can be considered as a potential therapeutic method against ischaemic tissue injury.[1][2] Repression of STAT-1 expression by human papillomavirus (HPV) oncoproteins E6 and E7 at transcription level is essential for genome amplification and maintenance of episomes, which is suggested to have a crucial role in viral pathogenesis.[3]

General description

The Phospho-Stat1 (pSer727) ELISA (Enzyme-Linked Immunosorbent Assay) kit is a very rapid, convenient and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates.

Immunogen

Stat1 (pTyr727) synthetic phosphopeptide, Recombinant Human STAT1

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Warning

hcodes

H290,H335

Hazard Classifications

Met. Corr. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

8A - Combustible corrosive hazardous materials

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Epigallocatechin-3-gallate inhibits STAT-1 activation and protects cardiac myocytes from ischemia/reperfusion-induced apoptosis.
Townsend PA
Faseb Journal, 18(13), 1621-1623 (2004)
Suppression of STAT-1 expression by human papillomaviruses is necessary for differentiation-dependent genome amplification and plasmid maintenance.
Hong S
Journal of Virology, 85(18), 9486-9494 (2011)
STAT-1: a novel regulator of apoptosis.
Stephanou A and Latchman DS
International Journal of Experimental Pathology, 84(6), 239-244 (2003)

Related Content

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service