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RAB0447

Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA Kit

for detection of phospho-stat3 (pTyr705) and pan-stat3 in human, mouse or rat cell and tissue lysates

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RAB0447-1KT

$902.00

$902.00

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

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species reactivity

human, mouse, rat

technique(s)

ELISA: suitable
capture ELISA: suitable

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... STAT3(6774)
mouse ... STAT3(20848)
rat ... STAT3(25125)

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RAB0444RAB0454RAB0443
Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA Kit for detection of phospho-stat3 (pTyr705) and pan-stat3 in human, mouse or rat cell and tissue lysates

Sigma-Aldrich

RAB0447

Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA Kit

Cell-Based ELISA for detecting phospho-STAT3 (pTyr705) in cultured cell lines 96 assays

Sigma-Aldrich

RAB0444

Cell-Based ELISA for detecting phospho-STAT3 (pTyr705) in cultured cell lines

Cell-Based phospho-STAT ELISA Samper Kit for detecting phospho-STAT1 (pTyr701), phospho-STAT3 (pTyr705), and phospho-STAT5 (pTyr694) in cultured cell lines 192 assays

Sigma-Aldrich

RAB0454

Cell-Based phospho-STAT ELISA Samper Kit for detecting phospho-STAT1 (pTyr701), phospho-STAT3 (pTyr705), and phospho-STAT5 (pTyr694) in cultured cell lines

Phospho-Stat1 (pTyr701) and pan-Stat1 ELISA Kit for detection of phospho-stat1 (pTyr701) and pan-stat1 in human or mouse cell and tissue lysates

Sigma-Aldrich

RAB0443

Phospho-Stat1 (pTyr701) and pan-Stat1 ELISA Kit

Gene Information

human ... STAT3(6774)
mouse ... STAT3(20848)
rat ... STAT3(25125)

Gene Information

human ... STAT3(6774)
mouse ... STAT3(20848)
rat ... STAT3(25125)

Gene Information

human ... STAT6(6778)
mouse ... STAT6(20852)
rat ... STAT6(362896)

Gene Information

human ... STAT1(6772)
mouse ... STAT1(20846)

species reactivity

human, mouse, rat

species reactivity

rat, human, mouse

species reactivity

rat, human, mouse

species reactivity

mouse, human

technique(s)

ELISA: suitable, capture ELISA: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

General description

Signal transducers and activators of transcription 3 (STAT3) is a transcription factor that belongs to the family of STAT proteins. The protein contains an Src homology 2 (SH2) domain for protein-protein interactions.[1] STAT3 is activated by phosphorylation on tyrosine 705 by c-Jun N-terminal kinases (JNKs), cytokine receptor-associated kinases, nonreceptor tyrosine kinases, and growth factor receptor tyrosine kinases, in response to growth factors and cytokines.[1][2] Phosphorylation of STAT3 is important for dimer formation and gene expression.[1][2] STAT3 mediates the expression of a variety of genes that are involved in cell proliferation and differentiation. It also aids in pro-cancer immunity.[3] The Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA (enzyme-linked immunosorbent assay) is a very rapid, convenient, and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates.
The Phospho-Stat3 (pTyr705) ELISA (Enzyme-Linked Immunosorbent Assay) kit is a very rapid, convenient and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates.

Immunogen

Stat3 (pTyr705) synthetic phosphopeptide, Recombinant Human Stat3

Application

Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA Kit has been used in enzyme-linked immunosorbent assay (ELISA) for quantitative measurement of phosphorylated signal transducer and activator of transcription3 (p-STAT3) in liver tissues.[4][5]

pictograms

Corrosion
GHS05

signalword

Warning

hcodes

H290

Hazard Classifications

Met. Corr. 1

Storage Class

8B - Non-combustible corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Targeting the Hepatocyte Growth Factor Receptor to Overcome Resistance to Targeted Therapies
Embryonic Stem Cell Protocols, 25-60 (2019)
Marisa Dolled-Filhart et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 9(2), 594-600 (2003-02-11)
Although a high frequency of tumors contain constitutively activated signal transducers and activators of transcription 3 (Stat3), its relationship to breast cancer and patient survival has not been determined in a large retrospective study of node-negative tumors. To further elucidate
Jinbo Yang et al.
Cancer research, 65(3), 939-947 (2005-02-12)
Signal transducer and activator of transcription 3 (STAT3) is phosphorylated on tyrosine residue 705 in response to growth factors or cytokines to form activated homodimers that drive gene expression. Because the stat3 promoter has a binding site for STAT3 dimers
Manar M Esmail et al.
Toxicology letters, 347, 23-35 (2021-05-08)
Liver fibrosis is the conjoint consequence of almost all chronic liver diseases. Cholestatic liver injury is a significant stimulus for fibrotic liver. This study was conducted to investigate the hepatoprotective effect of niclosamide as a NOTCH inhibitor and on the
Hyo Jeong Kang et al.
Oncotarget, 8(16), 27263-27276 (2017-05-04)
The non-receptor tyrosine phosphatase SHP2 has scaffolding functions in signal transduction cascades downstream of growth receptors. A recent study suggested that SHP2 acts as a tumor suppressor during hepatocellular carcinoma (HCC) development. Herein we examined whether SHP2 links the HBx-NF-κB

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