RAB0782

Mouse Eng / Endoglin ELISA Kit

Name: Mouse Eng / Endoglin ELISA Kit
Brand: SIGMA
Price: 622 USD

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96 WELLS

$622.00

Usually Ships in 4 Weeks. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

About This Item

UNSPSC Code:

41116158

NACRES:

NA.32

Key Documents

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species reactivity

mouse

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type serum
sample type cell culture supernatant(s)
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 16 pg/mL
standard curve range: 16.38-4000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Eng(13805)

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Show Differences

1 of 4

This Item	RAB0807	RAB0794	RAB0765
Sigma-Aldrich RAB0782 Mouse Eng / Endoglin ELISA Kit	Sigma-Aldrich RAB0807 Mouse Il17rb / Interleukin-17 Receptor B ELISA Kit	Sigma-Aldrich RAB0794 Mouse Met / Hepatocyte Growth Factor Receptor ELISA Kit	Sigma-Aldrich RAB0765 Mouse Cd27 / CD27 Antigen ELISA Kit
species reactivity mouse	species reactivity mouse	species reactivity mouse	species reactivity mouse
Gene Information mouse ... Eng(13805)	Gene Information mouse ... Il17rb(50905)	Gene Information mouse ... Met(17295)	Gene Information mouse ... Cd27(21940)
assay range inter-assay cv: <12% intra-assay cv: <10% sensitivity: 16 pg/mL standard curve range: 16.38-4000 pg/mL	assay range inter-assay cv: <12% intra-assay cv: <10% sensitivity: 0.2 ng/mL standard curve range: 0.200-50 ng/mL	assay range inter-assay cv: <12% intra-assay cv: <10% sensitivity: 0.08 ng/mL standard curve range: 0.082-20 ng/mL	assay range inter-assay cv: <12% intra-assay cv: <10% sensitivity: 32 pg/mL standard curve range: 32.77-8000 pg/mL
input sample type serum sample type cell culture supernatant(s) sample type plasma	input sample type cell culture supernatant(s) sample type serum sample type plasma	input sample type cell culture supernatant(s) sample type plasma sample type serum	input sample type cell culture supernatant(s) sample type serum sample type plasma
technique(s) ELISA: suitable	technique(s) ELISA: suitable	technique(s) ELISA: suitable	technique(s) ELISA: suitable
detection method colorimetric	detection method colorimetric	detection method colorimetric	detection method colorimetric

General description

The antibody pair provided in this kit recognizes Mouse Endoglin.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit Components Also Available Separately

Product No.

Description

SDS

RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS

RABSTOP3ELISA Stop Solution (Item I)SDS

RABWASH420X Wash Buffer (Item B)SDS

pictograms

GHS05

signalword

Warning

hcodes

H290

pcodes

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

SAMPLE

0302C0559

1013B0559

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Regulation and role of endoglin in cholesterol-induced endothelial and vascular dysfunction in vivo and in vitro.

Matej Vicen et al.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(5), 6099-6114 (2019-02-13)

Our objective was to investigate the effect of cholesterol [hypercholesterolemia and 7-ketocholesterol (7K)] on endoglin (Eng) expression and regulation with respect to endothelial or vascular dysfunction in vivo and in vitro. In vivo experiments were performed in 2-mo-old atherosclerosis-prone apolipoprotein

Soluble endoglin production is upregulated by oxysterols but not quenched by pravastatin in primary placental and endothelial cells.

F C Brownfoot et al.

Placenta, 35(9), 724-731 (2014-07-22)

Preeclampsia is a serious pregnancy complication. Soluble endoglin (sEng) is released from the placenta and contributes to the maternal endothelial dysfunction seen in preeclampsia. Recently oxysterols, which activate the Liver X Receptor (LXR), have been implicated in producing sEng, by

Endoglin promotes angiogenesis in cell- and animal-based models of retinal neovascularization.

Joshua M Barnett et al.

Investigative ophthalmology & visual science, 55(10), 6490-6498 (2014-08-28)

We investigated endoglin expression in hypoxic microvascular endothelial cells and retinal endoglin expression in rats that develop experimental oxygen-induced retinopathy (OIR). We also tested neutralizing antibodies (Abs) against endoglin (anti-CD105 Ab) and VEGF (anti-VEGF Ab) either alone or in combination

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