RDD004

PIPES

Name: PIPES
Brand: SIGMA
Price: 672 USD
Availability: InStock

anhydrous, free-flowing, Redi-Dri^™, ≥99%

Synonym(s):

1,4-Piperazinediethanesulfonic acid, Piperazine-1,4-bis(2-ethanesulfonic acid), Piperazine-N,N′-bis(2-ethanesulfonic acid)

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About This Item

Empirical Formula (Hill Notation):

C₈H₁₈N₂O₆S₂

CAS Number:

5625-37-6

Molecular Weight:

302.37

Beilstein/REAXYS Number:

817713

EC Number:

227-057-6

MDL number:

MFCD00006159

UNSPSC Code:

12161700

PubChem Substance ID:

329824217

NACRES:

NA.25

Key Documents

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grade

anhydrous

Quality Level

100

product line

Redi-Dri^™

assay

≥99%

form

crystalline powder

quality

free-flowing

loss

≤1.0% loss on drying, 110 degrees Celcius

useful pH range

6.1-7.5

pKa (25 °C)

6.8

mp

>300 °C (lit.)

solubility

1 M NaOH: 20 + 80 mL g, clear, colorless

SMILES string

OS(=O)(=O)CCN1CCN(CC1)CCS(O)(=O)=O

InChI

1S/C8H18N2O6S2/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16/h1-8H2,(H,11,12,13)(H,14,15,16)

InChI key

IHPYMWDTONKSCO-UHFFFAOYSA-N

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Show Differences

1 of 4

This Item	80635	P3768	P1851
Sigma-Aldrich RDD004 PIPES	Sigma-Aldrich 80635 PIPES	Sigma-Aldrich P3768 PIPES disodium salt	Sigma-Aldrich P1851 PIPES
assay ≥99%	assay ≥99.5% (T)	assay ≥99% (titration)	assay -
grade anhydrous	grade for molecular biology	grade -	grade BioPerformance Certified, for molecular biology
product line Redi-Dri^™	product line BioXtra	product line -	product line -
Quality Level 100	Quality Level 100	Quality Level 200	Quality Level 400
form crystalline powder	form powder	form crystalline powder	form crystalline powder
solubility 1 M NaOH: 20 + 80 mL g, clear, colorless	solubility 0.1 M NaOH: 0.1 M at 20 °C, clear, colorless	solubility water: 0.5 g/mL, clear, colorless	solubility 1 M NaOH: 20 + 80 mL g, clear, colorless, soluble

Legal Information

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Hydrogen sulfide deactivates common nitrobenzofurazan-based fluorescent thiol labeling reagents.

Leticia A Montoya et al.

Analytical chemistry, 86(12), 6032-6039 (2014-05-24)

Sulfhydryl-containing compounds, including thiols and hydrogen sulfide (H2S), play important but differential roles in biological structure and function. One major challenge in separating the biological roles of thiols and H2S is developing tools to effectively separate the reactivity of these

Allelic expression mapping across cellular lineages to establish impact of non-coding SNPs.

Veronique Adoue et al.

Molecular systems biology, 10, 754-754 (2014-10-19)

Most complex disease-associated genetic variants are located in non-coding regions and are therefore thought to be regulatory in nature. Association mapping of differential allelic expression (AE) is a powerful method to identify SNPs with direct cis-regulatory impact (cis-rSNPs). We used

Low-intensity repetitive transcranial magnetic stimulation improves abnormal visual cortical circuit topography and upregulates BDNF in mice.

Kalina Makowiecki et al.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(32), 10780-10792 (2014-08-08)

Repetitive transcranial magnetic stimulation (rTMS) is increasingly used as a treatment for neurological and psychiatric disorders. Although the induced field is focused on a target region during rTMS, adjacent areas also receive stimulation at a lower intensity and the contribution

Interrogation of allelic chromatin states in human cells by high-density ChIP-genotyping.

Nicholas Light et al.

Epigenetics, 9(9), 1238-1251 (2014-07-24)

Allele-specific (AS) assessment of chromatin has the potential to elucidate specific cis-regulatory mechanisms, which are predicted to underlie the majority of the known genetic associations to complex disease. However, development of chromatin landscapes at allelic resolution has been challenging since

Ratiometric measurement of hydrogen sulfide and cysteine/homocysteine ratios using a dual-fluorophore fragmentation strategy.

Matthew D Hammers et al.

Analytical chemistry, 86(14), 7135-7140 (2014-06-18)

Hydrogen sulfide (H2S) is an integral signaling molecule in biology with complex generation, translocation, and metabolism processes that are intertwined with cellular thiols. Differentiating the complex interplay between H2S and biological thiols, however, remains challenging due to the difficulty of

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Redi-Dri™ – The World of Free-flowing Hygroscopic Products

Redi-Dri™ prevents hygroscopic powders, such as inorganic salts, from absorbing moisture and forming clumps, leaving the salts free-flowing every time.

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