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RES0114M-A7

SAFC

MES sodium salt

Synonym(s):
4-Morpholineethanesulfonic acid sodium salt, 2-(N-Morpholino)ethanesulfonic acid sodium salt
Empirical Formula (Hill Notation):
C6H12NNaO4S
CAS Number:
Molecular Weight:
217.22
Beilstein:
3765682
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Quality Level

biological source

synthetic

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

Endotoxin and microbial, tested

useful pH range

5.5-6.7

pKa 

6.1

suitability

suitable for manufacturing use

foreign activity

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

SMILES string

[Na+].[O-]S(=O)(=O)CCN1CCOCC1

InChI

1S/C6H13NO4S.Na/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);/q;+1/p-1

InChI key

IRHWMYKYLWNHTL-UHFFFAOYSA-M

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Application

MES Sodium is a biological buffer often referred to as a “Good′s” buffer. The pKa of MES is 5.96 which makes MES an ideal candidate for cell culture media and protein based buffer formulations to maintain a stable environment in solution. MES Sodium is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.

MES Sodium is used in cell culture media, biopharmaceutical buffer formulations both upstream and downstream and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components.

Packaging

Product is available in the following package sizes:
RES0114M-A701X: 100g container
RES0114M-A702X 1kg container
RES0114M-A704X: 10kg container
RES0114M-A705X: 25kg container

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Christian Engelbrekt et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 11(13), 2844-2853 (2010-08-18)
Monodisperse platinum nanoparticles (PtNPs) were synthesized by a green recipe. Glucose serves as a reducing agent and starch as a stabilization agent to protect the freshly formed PtNP cores in buffered aqueous solutions. Among the ten buffers studied, 2-(N-morpholino)ethanesulfonic acid
Kefang Xie et al.
Acta crystallographica. Section D, Biological crystallography, 61(Pt 10), 1386-1394 (2005-10-06)
The NNA7 Fab antibody fragment recognizes the human N-type blood-group antigen comprised of the N-terminal glycopeptide of glycophorin A (GPA). A mutant form of this Fab fragment, NNA7-G91S, exhibits markedly reduced antigen binding. To provide insight into how these Fab
Pasi S Vuorinen et al.
Journal of chromatography. A, 990(1-2), 45-52 (2003-04-11)
A contactless conductivity detector integrated into the capillary cassette of Agilent (3D)CE equipment is described. The detector is user-friendly, compact and easily modified. The UV detector of the (3D)CE equipment is available parallel with the contactless conductivity detector increasing the
Ekta G Ahuja et al.
Acta crystallographica. Section D, Biological crystallography, 60(Pt 6), 1129-1131 (2004-05-26)
Phenazines are broad-spectrum antibiotic metabolites produced by organisms such as Pseudomonas and Streptomyces. Phenazines have been shown to enhance microbial competitiveness and the pathogenic potential of the organisms that synthesize them. PhzA (163 residues, approximate molecular weight 18.7 kDa) is
Padmavati Venkataraman et al.
The Journal of biological chemistry, 280(22), 21463-21472 (2005-03-24)
The influenza virus M2 proton-selective ion channel activity facilitates virus uncoating, a process that occurs in the acidic environment of the endosome. The M2 channel causes acidification of the interior of the virus particle, which results in viral protein-protein dissociation.

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