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RES10070-A7

SAFC

L-Asparagine monohydrate

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Synonym(s):
(S)-(+)-2-Aminosuccinamic acid, (S)-2-Aminosuccinic acid 4-amide, L-Aspartic acid 4-amide
Linear Formula:
NH2COCH2CH(NH2)COOH · H2O
CAS Number:
Molecular Weight:
150.13
Beilstein:
1723527
EC Number:
MDL number:
NACRES:
NA.21

biological source

synthetic

Assay

98.5-101.0% dry basis

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin and microbial, tested

mp

233-235 °C (lit.)

suitability

suitable for manufacturing use

foreign activity

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

SMILES string

[H]O[H].N[C@@H](CC(N)=O)C(O)=O

InChI

1S/C4H8N2O3.H2O/c5-2(4(8)9)1-3(6)7;/h2H,1,5H2,(H2,6,7)(H,8,9);1H2/t2-;/m0./s1

InChI key

RBMGJIZCEWRQES-DKWTVANSSA-N

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This Item
A4284A70941.01566
L-Asparagine monohydrate

SAFC

RES10070-A7

L-Asparagine monohydrate

-
L-Asparagine monohydrate BioReagent, suitable for cell culture

Sigma-Aldrich

A4284

L-Asparagine monohydrate

-
L-Asparagine monohydrate from non-animal source, BioReagent, suitable for cell culture, ≥98.0%

Sigma-Aldrich

A7094

L-Asparagine monohydrate

Essential+ Grade
Millipore

Millipore

1.01566

L-Asparagine monohydrate

-
form

powder

form

powder

form

powder

form

solid

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

-

impurities

endotoxin and microbial, tested

impurities

-

impurities

endotoxin, tested

impurities

-

mp

233-235 °C (lit.)

mp

233-235 °C (lit.)

mp

233-235 °C (lit.)

mp

215-217 °C (decomposes)

Quality Level

400

Quality Level

300

Quality Level

300

Quality Level

100

General description

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

Application

L-Asparagine is an essential amino acid. It is used as a cell culture media component and raw material for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Packaging

Product is available in the following package sizes:
RES10070-A701X: 100g container
RES10070-A702X: 1kg container
RES10070-A704X: 10kg container

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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-
25G
Pack Size/Quantity

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L-Asparagine ≥98% (HPLC)

Sigma-Aldrich

A0884

L-Asparagine

Asparagine anhydrous United States Pharmacopeia (USP) Reference Standard

USP

1043502

Asparagine anhydrous

L-Aspartic acid

SAFC

A5474

L-Aspartic acid

L-Asparagine phyproof® Reference Substance

PHL80905

L-Asparagine

Deia Abd El-Hady et al.
Food chemistry, 188, 551-558 (2015-06-05)
Acrylamide (AA) is a known lethal neurotoxin and carcinogen. AA is formed in foods during the browning process by the Maillard reaction of glucose (GL) with asparagine (AS). For the first time, the simultaneous online preconcentration and separation of AA
Gustavo Luis Leonardo Scalone et al.
Journal of agricultural and food chemistry, 63(22), 5364-5372 (2015-05-15)
Pyrazines are specific Maillard reaction compounds known to contribute to the unique aroma of many products. Most studies concerning the generation of pyrazines in the Maillard reaction have focused on amino acids, while little information is available on the impact
Han Yao et al.
Journal of pharmaceutical and biomedical analysis, 117, 232-239 (2015-09-18)
L-asparaginase is an effective anti-tumor agent for acute lymphoblastic leukemia. This work presents the development of an activity determination of L-ASNase preparations for pharmaceutical quality control purposes, in accordance with analytical Quality by Design principles. Critical method attributes, the absorbance

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