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S0389

Sigma-Aldrich

Sucrose

for molecular biology, ≥99.5% (GC)

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Synonym(s):
α-D-Glc-(1→2)-β-D-Fru, α-D-Glucopyranosyl β-D-fructofuranoside, β-D-Fructofuranosyl-α-D-glucopyranoside, D(+)-Saccharose, Sugar
Empirical Formula (Hill Notation):
C12H22O11
CAS Number:
Molecular Weight:
342.30
Beilstein:
90825
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.31

biological source

sugar cane

Quality Level

grade

for molecular biology

Assay

≥99.5% (GC)

form

crystals

technique(s)

HPLC: suitable
cryopreservation: suitable
electron microscopy: suitable
enzyme immunoassay: suitable
gas chromatography (GC): suitable
immunohistochemistry: suitable

impurities

≤0.1% free glucose

color

white

useful pH range

5.5-7 (25 °C, 342 g/L)

mp

185-187 °C (lit.)

solubility

H2O: soluble 50 g + 50 mL

cation traces

heavy metals (as Pb): ≤5 ppm

absorption

≤0.15 at 280 at 50%
≤0.20 at 260 at 50%

suitability

suitable for molecular biology

application(s)

agriculture
agriculture
life science and biopharma
metabolomics
sample preservation

foreign activity

DNase, RNase, protease, none detected

storage temp.

room temp

SMILES string

OC[C@H]1O[C@H](O[C@]2(CO)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C12H22O11/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12/h4-11,13-20H,1-3H2/t4-,5-,6-,7-,8+,9-,10+,11-,12+/m1/s1

InChI key

CZMRCDWAGMRECN-UGDNZRGBSA-N

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S7903S9378S5390
Sucrose for molecular biology, ≥99.5% (GC)

Sigma-Aldrich

S0389

Sucrose

-
Sucrose BioXtra, ≥99.5% (GC)

Sigma-Aldrich

S7903

Sucrose

Premium Grade
Sucrose ≥99.5% (GC)

Sigma-Aldrich

S9378

Sucrose

-
Sucrose ≥99% (GC), Grade I, suitable for plant cell culture

Sigma-Aldrich

S5390

Sucrose

-
grade

for molecular biology

grade

-

grade

-

grade

-

assay

≥99.5% (GC)

assay

≥99.5% (GC)

assay

≥99.5% (GC)

assay

≥99% (GC)

form

crystals

form

crystals

form

crystals

form

crystals

technique(s)

HPLC: suitable, cryopreservation: suitable, electron microscopy: suitable, enzyme immunoassay: suitable, gas chromatography (GC): suitable, immunohistochemistry: suitable

technique(s)

gas chromatography (GC): suitable

technique(s)

gas chromatography (GC): suitable

technique(s)

cell culture | plant: suitable

impurities

≤0.1% free glucose

impurities

Insoluble matter, passes filter test

impurities

≤5 ppm heavy metals

impurities

≤5 ppm heavy metals (as lead)

General description

Sucrose, a disaccharide composed of glucose and fructose, serves as an energy source in various biological processes. In cell biology, sucrose acts as a cryoprotectant, preserving cell viability during freezing and thawing. It is also added as a supplement in culture media, aiding in maintaining osmotic balance and enhancing cell survival.In molecular biology, sucrose is crucial in gradient solutions for DNA and RNA purification and in density centrifugation for organelle separation.

Application

Sucrose has been used:
  • to perform cryoprotection for kidney tissues
  • as a component in the solid germination medium to germinate pollen grains
  • in the triphenyl-tetrazolium chloride (TTC) test to check the viability of pollen grains
  • in the cryoprotection of fixed brain tissues for immunohistochemistry

Biochem/physiol Actions

Sucrose is used as a transport and storage molecule in most plants due to its limited chemical reactivity. It can be used to prepare density gradients for the separation of cell/organelle. Sucrose can be used in the plant, insect, and bacterial culture media as a supplement. In addition, sucrose can also be used in several enzymatic assays.

Features and Benefits

  • Ideal for Molecular Biology, Cell Biology and Biochemical research
  • Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications
  • Tested for DNase, RNase, and proteases
  • Molecular biology grade sucrose, sourced from sugar cane

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Plant science : an international journal of experimental plant biology, 221-222, 59-68 (2014-03-25)
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