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S1820

Sigma-Aldrich

Ser-Phe-Leu-Leu-Arg-Asn-amide trifluoroacetate salt

≥98% (HPLC), lyophilized powder

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Synonym(s):
PAR-1 (Protease-Activated Receptor) Selective Activating Peptide, PAR1-AP, SFLLRN-NH2
Linear Formula:
C34H57N11O8 · x CF3COOH
CAS Number:
Molecular Weight:
747.89 (free base basis)
MDL number:
PubChem Substance ID:
NACRES:
NA.32

Quality Level

assay

≥98% (HPLC)

form

lyophilized powder

color

white

UniProt accession no.

storage temp.

−20°C

SMILES string

OC(=O)C(F)(F)F.CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(N)=O

InChI

1S/C34H57N11O8.C2HF3O2/c1-18(2)13-24(31(51)41-22(11-8-12-40-34(38)39)30(50)42-23(28(37)48)16-27(36)47)44-32(52)25(14-19(3)4)45-33(53)26(43-29(49)21(35)17-46)15-20-9-6-5-7-10-20;3-2(4,5)1(6)7/h5-7,9-10,18-19,21-26,46H,8,11-17,35H2,1-4H3,(H2,36,47)(H2,37,48)(H,41,51)(H,42,50)(H,43,49)(H,44,52)(H,45,53)(H4,38,39,40);(H,6,7)/t21-,22-,23-,24-,25-,26-;/m0./s1

InChI key

YICKZNIVMKPQPD-POCCEKOUSA-N

Gene Information

human ... IGF1R(3480)

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This Item
S9192S7152S9317
Ser-Leu-Ile-Gly-Lys-Val-amide ≥95% (HPLC), solid

S9192

Ser-Leu-Ile-Gly-Lys-Val-amide

form

lyophilized powder

form

solid

form

powder

form

solid

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Gene Information

human ... IGF1R(3480)

Gene Information

mouse ... Insrr(23920)

Gene Information

-

Gene Information

-

UniProt accession no.

P08069

UniProt accession no.

Q9WTL4

UniProt accession no.

-

UniProt accession no.

-

color

white

color

-

color

white

color

-

Amino Acid Sequence

Ser-Phe-Leu-Leu-Arg-Asn-NH2

Application

Ser-Phe-Leu-Leu-Arg-Asn-amide trifluoroacetate salt has been used as a protease-activated receptor 1 (PAR-1) selective activating peptide.

Biochem/physiol Actions

Ser-Phe-Leu-Leu-Arg-Asn-amide trifluoroacetate salt (SFLLRN) acts as a protease-activated receptor 1 (PAR-1) specific agonist peptide.
Thrombin receptor activating peptide (TRAP).

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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