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MilliporeSigma

S2067

S9 from Liver, Pooled

from rat(Sprague-Dawley), male

Synonym(s):

Liver S9 Fraction, S9 Liver Extract

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1 VIAL

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About This Item

NACRES:
NA.47
UNSPSC Code:
12161501

Key Documents

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biological source

rat (Sprague-Dawley)

packaging

vial of ~20 mg

UniProt accession no.

B0BN68

shipped in

dry ice

storage temp.

−70°C

Quality Level

200

Gene Information

rat ... Mrps9(301371)

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1 of 4

This Item
S2192M9566M0317
S9 from Liver, Pooled from rat(Sprague-Dawley), male

Sigma-Aldrich

S2067

S9 from Liver, Pooled

S9 from Liver, Pooled from mouse(CD-1), male, 20 mg/mL protein basis, vial of 1.0 mL

Sigma-Aldrich

S2192

S9 from Liver, Pooled

Sigma-Aldrich

Sigma-Aldrich

M9566

Microsomes from Liver, Pooled

Sigma-Aldrich

Sigma-Aldrich

M0317

Microsomes from Liver, Pooled

biological source

rat (Sprague-Dawley)

biological source

mouse (CD-1)

biological source

mouse (CD-1)

biological source

human

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

Gene Information

rat ... Mrps9(301371)

Gene Information

mouse ... Rps9(76846)

Gene Information

mouse ... Mgst1(56615)

Gene Information

-

UniProt accession no.

B0BN68

UniProt accession no.

Q6ZWN5

UniProt accession no.

Q91VS7

UniProt accession no.

-

packaging

vial of ~20 mg

packaging

vial of 1.0 mL

packaging

vial of ~10 mg

packaging

vial of ~10 mg

storage temp.

−70°C

storage temp.

−70°C

storage temp.

−70°C

storage temp.

−70°C

Application

S9 from Liver, Pooled has been used in metabolic activation in Salmonella typhimurium strains.[1]

Biochem/physiol Actions

Post-mitochondrial supernatant fraction from homogenized liver. Source of drug metabolizing enzymes including P-450, these pools are useful in the study of xenobiotic metabolism and drug interactions.
The hepatic S9 pools from a variety of biological sources represent the post-mitochondrial supernatant fraction from homogenized liver. Known to be a rich source of drug metabolizing enzymes including P-450, these pools are useful in the study of xenobiotic metabolism and drug interactions.
They are used in the Ames test, which is a method that uses bacteria to test if a given chemical causes mutations in the genetic material of a given test organism.[2][3]

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000458939
0000458939
0000424570
0000424570
0000258131

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Genotoxicity evaluation of locally produced dental porcelain-An in vitro study using the Ames and Comet assays
Noushad M, et al.
Toxicology in vitro, 23(6), 1145-1150 (2009)
Milena Lopes Francisco Bittencourt et al.
Life sciences, 256, 117977-117977 (2020-07-01)
Silibinin is the major component of flavonolignans complex mixture (Silymarin), which is obtained from Silybum marianum (L.) Gaertn. Despite several reports about silibinin, little is known about its effects on gastric diseases. Then, the present study aims to evaluate the
Leonara Fayer et al.
Toxicology research, 10(3), 511-522 (2021-06-19)
The titanium dioxide nanoparticles (NPs) have been applied to biomedical, pharmaceutical, and food additive fields. However, the effect on health and the environment are conflicting; thus, it has been reviewing several times. In this context, establishing standard robust protocols for
The Ames Salmonella/microsome mutagenicity assay.
Mortelman K and Zeiger E
Mutation Research, 455(1-2), 29-60 (2000)
Esra Erikel et al.
Environmental and molecular mutagenesis, 64(5), 291-308 (2023-05-10)
Amygdalin (AMY), a plant secondary metabolite containing nitrile, is a major component of the seeds of Rosaceae family plants. It is known that this compound has many pharmacological activities such as cancer prevention, antipyretic, and cough suppressant. In this study
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