S4311

L-Serine

from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

• Synonym(s): L Serine, (S)-2-Amino-3-hydroxypropionic acid
• Linear Formula: HOCH₂CH(NH₂)CO₂H
• CAS Number: 56-45-1
• Molecular Weight: 105.09
• Beilstein: 1721404
• EC Number: 200-274-3
• MDL number: MFCD00064224
• eCl@ss: 32160406
• PubChem Substance ID: 24899599
• NACRES: NA.26

Properties

• biological source: non-animal source
• Quality Level: 200
• Agency: USP/NF; meets EP testing specifications; meets USP testing specifications
• Assay: 98.5-101.0%
• form: powder
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, tested
• color: white
• mp: 222 °C (dec.) (lit.)
• solubility: H₂O: 50 mg/mL
• application(s): pharmaceutical (small molecule)
• SMILES string: N[C@@H](CO)C(O)=O
• InChI: 1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1
• InChI key: MTCFGRXMJLQNBG-REOHCLBHSA-N

Description

Application

L-Serine has been used as a supplement in a medium to culture Chinese hamster ovary TF 70R cell line and in mouse embryonic fibroblast (MEF)-media.

Biochem/physiol Actions

L-Serine is a non-essential amino acid that acts as a precursor for nucleotide synthesis. It has roles in the development and function of the central nervous system.

Precursor of glycine by serine hydroxymethyltransferase.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves