S7382

Sigma-Aldrich

Sulfaquinoxaline sodium salt

≥92.5%

Empirical Formula (Hill Notation):
C14H11N4NaO2S
CAS Number:
Molecular Weight:
322.32
Beilstein/REAXYS Number:
290026
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.85

Quality Level

assay

≥92.5%

form

powder

color

white to yellow

solubility

H2O: soluble 50 mg/mL

Mode of action

DNA synthesis | interferes
enzyme | inhibits

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

SMILES string

Nc1ccc(cc1)S(=O)(=O)N([Na])c2cnc3ccccc3n2

InChI

1S/C14H11N4O2S.Na/c15-10-5-7-11(8-6-10)21(19,20)18-14-9-16-12-3-1-2-4-13(12)17-14;/h1-9H,15H2;/q-1;+1

InChI key

WXUQBKOBXREBBX-UHFFFAOYSA-N

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General description

Chemical structure: sulfonamide

Application

Sulfaquinoxaline is a veterinary medicine used to treat coccidiosis. It is a protective agent against upper respiratory infections of poultry and a prophylactic against coccidiosis.

Biochem/physiol Actions

Sulfaquinoxaline is an ionophorous antibiotic that inhibits vitamin K epoxidase (epoxide reductase, menadione epoxide reductase) and quinone reductase.

Packaging

10G,25G

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

hazcat

Acute Tox. 4 Oral - Skin Sens. 1

storage_class_code

11 - Combustible Solids

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Vanessa Ribeiro Urbano et al.
International journal of environmental research and public health, 18(3) (2021-01-28)
Sulfaquinoxaline (SQX) has been detected in environmental water samples, where its side effects are still unknown. To the best of our knowledge, its oxidation by Fenton and photo-Fenton processes has not been previously reported. In this study, SQX oxidation, mineralization...
The effect of sulfaquinoxaline administration on metabolism of vitamin A and carotene and on hemoglobin young dairy calves.
M RONNING et al.
Journal of animal science, 9(3), 314-320 (1950-08-01)
Lilya Boudriche et al.
Water environment research : a research publication of the Water Environment Federation, 91(11), 1412-1419 (2019-05-06)
This study evaluates the efficiency of sulfate radicals used in advanced oxidation process in water treatment. The targeted pollutant is an antibiotic, sulfaquinoxaline (SQ-Na) sodium, widely used in the veterinary field. The results show a degradation of SQ-Na until 90%...
H D Chapman
Poultry science, 88(4), 813-815 (2009-03-12)
"Continuous feeding of low concentrations of sulfaquinoxaline for the control of coccidiosis in poultry" by L. C. Grumbles, J. P. Delaplane, and T. C. Higgins [Poult. Sci. (1948) 27:605-608] was the first paper to demonstrate that it was possible to...
Ahmad Soleymanpour et al.
Materials science & engineering. C, Materials for biological applications, 58, 504-509 (2015-10-20)
A potentiometric carbon paste sensor was fabricated for determination of sulfaquinoxaline (SQX) based on the use of ion-association complex of sulfaquinoxaline sodium with 2,3,5-triphenyltetrazolium chloride. The proposed sensor exhibited Nernstian slope of 58.4 ± 0.3 mV per decade for sulfaquinoxaline...

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