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S9512

Sigma-Aldrich

Succinic acid

greener alternative

BioReagent, BioRenewable, suitable for cell culture, suitable for insect cell culture

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Synonym(s):
Butanedioic acid
Linear Formula:
HOOCCH2CH2COOH
CAS Number:
Molecular Weight:
118.09
Beilstein:
1754069
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.71

Quality Level

product line

BioReagent

Assay

≥99.0% ( with NaOH, titration)

form

powder

greener alternative product characteristics

Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable

bp

235 °C (lit.)

mp

184-186 °C (lit.)

solubility

water: 100 mg/mL, clear, colorless

density

1.564 g/cm3 at 15 °C

greener alternative category

SMILES string

OC(=O)CCC(O)=O

InChI

1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

InChI key

KDYFGRWQOYBRFD-UHFFFAOYSA-N

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1 of 4

This Item
S75011407914080
Succinic acid BioReagent, BioRenewable, suitable for cell culture, suitable for insect cell culture

Sigma-Aldrich

S9512

Succinic acid

Essential+ Grade
Succinic acid ReagentPlus®, BioRenewable, ≥99.0%

Sigma-Aldrich

S7501

Succinic acid

-
Succinic acid puriss. p.a., ACS reagent, ≥99.5% (T)

Sigma-Aldrich

14079

Succinic acid

-
Succinic acid purum p.a., ≥99.0% (T)

Sigma-Aldrich

14080

Succinic acid

-
form

powder

form

-

form

-

form

-

bp

235 °C (lit.)

bp

235 °C (lit.)

bp

235 °C (lit.)

bp

235 °C (lit.)

mp

184-186 °C (lit.)

mp

184-186 °C (lit.)

mp

184-186 °C (lit.), 185-191 °C

mp

184-186 °C (lit.), 185-188 °C

solubility

water: 100 mg/mL, clear, colorless

solubility

H2O: soluble 1 g/10 mL

solubility

methanol: soluble 0.4 g/10 mL

solubility

methanol: soluble 0.4 g/10 mL

density

1.564 g/cm3 at 15 °C

density

-

density

-

density

-

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is biobased and thus aligns with "Use of Renewable Feedstocks". Click here for more information.

Application

Use as a TCA (Krebs cycle) supplement in insect cell culture applications.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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-
25G
Pack Size/Quantity

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705578-5MG-PW

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SAFC

1.00681

Succinic acid

Succinic acid United States Pharmacopeia (USP) Reference Standard

USP

1623411

Succinic acid

Muhammad Fariz Ali et al.
Pathogens (Basel, Switzerland), 9(9) (2020-09-10)
To gain insight into how pathogens adapt to new hosts, Cryptococcus neoformans (H99W) was serially passaged in Galleria mellonella. The phenotypic characteristics of the passaged strain (P15) and H99W were evaluated. P15 grew faster in hemolymph than H99W, in vitro
Corey Osto et al.
Current protocols in cell biology, 89(1), e116-e116 (2020-12-16)
Measuring oxygen consumption allows for the role of mitochondrial function in biological phenomena and mitochondrial diseases to be determined. Although respirometry has become a common approach in disease research, current methods are limited by the necessity to process and measure
Monika Bambouskova et al.
Cell reports, 34(10), 108756-108756 (2021-03-11)
Itaconate is a unique regulatory metabolite that is induced upon Toll-like receptor (TLR) stimulation in myeloid cells. Here, we demonstrate major inflammatory tolerance and cell death phenotypes associated with itaconate production in activated macrophages. We show that endogenous itaconate is
José Manuel Otero et al.
PloS one, 8(1), e54144-e54144 (2013-01-26)
Saccharomyces cerevisiae is the most well characterized eukaryote, the preferred microbial cell factory for the largest industrial biotechnology product (bioethanol), and a robust commerically compatible scaffold to be exploitted for diverse chemical production. Succinic acid is a highly sought after
Susan Jahn et al.
Biochimica et biophysica acta, 1833(12), 2879-2889 (2013-07-28)
To investigate a possible role of the nitrogen-PTS (PTS(Ntr)) in controlling carbon metabolism, we determined the growth of Escherichia coli LJ110 and of isogenic derivatives, mutated in components of the PTS(Ntr), on different carbon sources. The PTS(Ntr) is a set

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