SAB1300769

Anti-SPP (N-term) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• Synonym(s): Anti-HIMP1 protein, Anti-HM13, Anti-Minor histocompatibility antigen H13, Anti-Presenilin-like protein 3, Anti-Signal peptide peptidase
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 200
• conjugate: unconjugated
• antibody form: IgG fraction of antiserum
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human
• technique(s): indirect ELISA: 1:1000
• NCBI accession no.: NP_848696
• UniProt accession no.: Q8TCT9-2
• shipped in: dry ice
• storage temp.: −20°C
• Gene Information: human ... SPP(81502)

Description

General description

SPP, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. This protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases.

Immunogen

SPP (NP_848696, 1-30)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human SPP.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable