SAB1300769

Sigma-Aldrich

Anti-SPP (N-term) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym(s):
Anti-HIMP1 protein, Anti-HM13, Anti-Signal peptide peptidase, Anti-Minor histocompatibility antigen H13, Anti-Presenilin-like protein 3
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

application(s)

indirect ELISA: 1:1000

conjugate

unconjugated

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... SPP(81502)

General description

SPP, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. This protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases.

Immunogen

SPP (NP_848696, 1-30)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human SPP.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

storage_class_code

12 - Non Combustible Liquids

WGK Germany

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

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